Market Size of Global Aptamers Industry
Study Period | 2019 - 2029 |
Base Year For Estimation | 2023 |
Forecast Data Period | 2024 - 2029 |
CAGR | 18.50 % |
Fastest Growing Market | Asia-Pacific |
Largest Market | North America |
Major Players*Disclaimer: Major Players sorted in no particular order |
Need a report that reflects how COVID-19 has impacted this market and its growth?
Aptamers Market Analysis
The Aptamers Market is expected to register a CAGR of 18.5% over the forecast period.
Globally, COVID-19 is an intractable health challenge resulting in an aberrant rate of morbidity and mortality. The mode of entry for SARS-CoV-2 into host cells occurs through clathrin-mediated endocytosis. As part of the efforts to mitigate COVID-19 infections, rapid and accurate detection methods, as well as vaccine and drug designs with SARS-CoV-2 targeting capabilities are critically needed. According to a research study by Caleb Acquah et al., published in Cellular and Molecular Bioengineering Journal, January 2021, globally, there is an urgent need to develop safe innovative biomedical technologies to mitigate the direct impact of COVID-19 on public health. Moreover, research advances into aptameric systems bode well with the fact that they can be engineered for the development of effective and affordable diagnostics, therapeutics, and prophylactic vaccines for SARS-CoV-2 and other infectious pathogens. Furthermore, according to a research study by Vamkudoth Koteswara Rao et al., published in Frontiers in Nanotechnology Journal, February 2021, the study results found that aptamer-based detection is the most specific, inexpensive, and rapid detection of COVID-19 without laboratory tools. In addition, more than 900 SARS-nCoV-2 test kits are in pipeline and a few test kits are developed using Aptamer technology.
Some of the factors that are driving the market growth include high advantage of aptamers compared to antibodies, advancements in the field of aptamer development technologies and growing investment in the companies and research institutes.
Numerous advantages offered by these small molecules, in comparison to established antibodies, have also led to higher demand for these molecules across a diverse range of medical applications. They are chemically synthesized, which eliminates batch-to-batch variation and demands less time for development. Along with this, continuous advancement in technologies is expected to stimulate market growth. According to a research study by Geanina Ștefan et al., published in Electrochimica Acta Journal April 2021, the study results found that aptamers have come into the spotlight as bio-mimetic molecular recognition elements in the field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics, and pharmaceutical analysis. Aptamers are composed of nucleic acid strands (DNA or RNA) that can specifically interact in a three-dimensional tailored design with the target molecule.
The market players are adopting various strategies such as product launches, developments. collaborations, partnerships, and expansions to increase market share. For instance, in August 2020, Aptamer Sciences Inc., in co-operation with POSTECH, discovered a number of aptamers that specifically bind to the COVID-19 spike protein using ViroSELEX technology, a unique aptamer discovery technology, and applied for a material patent. However, many aptamers have failed to meet the requisite safety and efficacy standards in clinical studies. Thus, companies had to terminate their clinical investigation during late-stage clinical studies. This factor is likely to affect the growth of this market negatively. In addition, other factors, such as unfavorable pharmacokinetic properties of aptamers and low awareness level and incomplete regulatory policies, may hamper the overall market growth.
Aptamers Industry Segmentation
As per the scope of the report, aptamers are short, single-stranded DNA or RNA (ssDNA or ssRNA) molecules, which can selectively bind to a specific target, including peptides, proteins, small molecules, carbohydrates, toxins, and even live cells. Aptamers assume various shapes, owing to their tendency to form helices or single-stranded loops. These molecules are extremely versatile and are used to bind targets with high specificity and selectivity. The aptamers market is segmented by Type (Nucleic Acid and Peptide), Application (Diagnostics, Therapeutics, Research and Development, and Other Applications), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions globally. The report offers the value (in USD million) for the above segments.
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Nucleic Acid | |
Peptide |
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Diagnostics | |
Therapeutics | |
Research and Development | |
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Global Aptamers Market Size Summary
The Aptamers Market is poised for significant growth, driven by the increasing demand for innovative biomedical technologies and the advantages of aptamers over traditional antibodies. Aptamers, which are nucleic acid strands capable of specific interactions with target molecules, are gaining traction in various medical applications, including diagnostics, therapeutics, and drug delivery. Their chemical synthesis offers consistency and rapid development, making them attractive for research and clinical applications. The market is witnessing a surge in investment and advancements in aptamer development technologies, which are expected to further propel market expansion. Despite challenges such as safety and efficacy concerns in clinical studies, the potential of aptamers in developing sensitive and specific biosensors for viral detection, including COVID-19, is driving interest and research in this field.
North America leads the Aptamers Market, supported by substantial research and development activities and high investment in aptamer technologies. The region's dominance is attributed to its robust infrastructure for biomedicine and personalized medicine, with the United States being a key player in aptamer-related R&D. The market is characterized by strategic initiatives such as collaborations, product launches, and partnerships among key players like Aptagen, LLC, and Aptamer Sciences Inc. These efforts aim to enhance market share and develop novel aptamer-based solutions for various applications. The ongoing research and clinical trials, including those targeting COVID-19 and cancer diagnostics, underscore the market's potential for growth and innovation over the forecast period.
Global Aptamers Market Size - Table of Contents
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1. MARKET DYNAMICS
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1.1 Market Overview
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1.2 Market Drivers
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1.2.1 High Advantage of Aptamers, Compared to Antibodies
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1.2.2 Advancements in the Field of Aptamer Development Technologies
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1.2.3 Growing Investment in the Companies and Research Institutes
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1.3 Market Restraints
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1.3.1 Unfavorable Pharmacokinetic Properties of Aptamers
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1.3.2 Low Awareness Level and Incomplete Regulatory Policies
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1.4 Porter's Five Force Analysis
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1.4.1 Threat of New Entrants
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1.4.2 Bargaining Power of Buyers/Consumers
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1.4.3 Bargaining Power of Suppliers
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1.4.4 Threat of Substitute Products
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1.4.5 Intensity of Competitive Rivalry
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2. MARKET SEGMENTATION
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2.1 By Type
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2.1.1 Nucleic Acid
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2.1.2 Peptide
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2.2 By Application
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2.2.1 Diagnostics
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2.2.2 Therapeutics
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2.2.3 Research and Development
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2.2.4 Other Applications
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2.3 Geography
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2.3.1 North America
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2.3.1.1 United States
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2.3.1.2 Canada
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2.3.1.3 Mexico
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2.3.2 Europe
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2.3.2.1 Germany
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2.3.2.2 United Kingdom
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2.3.2.3 France
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2.3.2.4 Italy
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2.3.2.5 Spain
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2.3.2.6 Rest of Europe
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2.3.3 Asia-Pacific
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2.3.3.1 China
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2.3.3.2 Japan
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2.3.3.3 India
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2.3.3.4 Australia
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2.3.3.5 South Korea
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2.3.3.6 Rest of Asia-Pacific
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2.3.4 Middle East and Africa
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2.3.4.1 GCC
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2.3.4.2 South Africa
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2.3.4.3 Rest of Middle East and Africa
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2.3.5 South America
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2.3.5.1 Brazil
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2.3.5.2 Argentina
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2.3.5.3 Rest of South America
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Global Aptamers Market Size FAQs
What is the current Global Aptamers Market size?
The Global Aptamers Market is projected to register a CAGR of 18.5% during the forecast period (2024-2029)
Who are the key players in Global Aptamers Market?
Aptagen, LLC, Aptamer Sciences Inc., Base Pair Biotechnologies Inc., Aptamer Group and Aptus Biotech S.L. are the major companies operating in the Global Aptamers Market.