Biguanides Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)

The Report Covers Global Biguanide Market Brands & Drug List and It is Segmented by Geography. The Market Provides the Value (in USD) for the Above-Mentioned Segments.

Biguanides Market Size

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Biguanides Market Summary
Study Period 2018 - 2029
Market Size (2024) USD 5.20 Billion
Market Size (2029) USD 5.76 Billion
CAGR (2024 - 2029) 2.07 %
Fastest Growing Market Middle East and Africa
Largest Market Asia-Pacific

Major Players

Biguanides Market Major Players

*Disclaimer: Major Players sorted in no particular order

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Biguanides Market Analysis

The Biguanides Market size is estimated at USD 5.20 billion in 2024, and is expected to reach USD 5.76 billion by 2029, growing at a CAGR of 2.07% during the forecast period (2024-2029).

Biguanides are a class of medications used to treat type 2 diabetes. They work by reducing the production of glucose that occurs during digestion. Metformin is the only biguanide currently available in most countries for treating diabetes. Glucophage (metformin) and Glucophage XR (metformin extended release) are well-known brand names for these drugs. Others include Fortamet, Glumetza, and Riomet. Metformin is also available in combination with several other types of diabetes medications, such as sulfonylureas.

The World Health Organization has put metformin on the list of essential medicines: "medicines that satisfy the priority health care needs of the population". Metformin is classified as a biguanide used for the treatment of type-2 diabetes. It is prescribed for its off-label use in people with conditions such as insulin resistance. 

Therefore, owing to the aforementioned factors the studied market is anticipated to witness growth over the analysis period.

Biguanides Market Trends

Rising diabetes prevalence globally

The global diabetes population is expected to rise by more than 1.9% over the forecast period.

According to the International Diabetes Federation, the adult diabetes population was approximately 537 million, and this number is expected to increase by 643 million in 2030. Obesity is considered one of the major factors contributing to the disease, primarily type-2 diabetes. Continued elevation in blood glucose levels in diabetes patients can contribute to progressive complications such as renal, nerve, and ocular damage. Type-2 diabetes is increasingly prevalent and associated with an increased risk for cardiovascular and renal disease. Along with lifestyle changes, metformin is usually the first-line pharmacotherapy.

Since the introduction of metformin in T2DM therapy, a huge number of patients have been treated successfully with this globally available medication, which has a favorable risk-benefit profile recommended by IDF guidelines as a first-line drug. Hence, metformin is still the most prescribed oral antidiabetic medication worldwide. Long-term positive experience with the use of metformin, strong evidence of clinical efficacy and safety, a high adherence rate, low cost, general availability, and cost-effectiveness are the contributing factors to the high market share.

Owing to the aforementioned factors and their increasing prevalence, it is likely that the market will continue to grow.

Biguanides Market, Type-2 Diabetes population in million, Global, 2017-2022

Asia-Pacific region holds the highest market share in the Biguanides Market in the current year

The Asia-Pacific region holds the highest market share of about 37.9% in the biguanides market in the current year.

The Asia-Pacific region has witnessed an alarming increase in the prevalence of diabetes in recent years. In developing countries such as China and India, the rate of diabetes is at an all-time high, mainly due to lifestyle changes. 

According to the International Diabetes Federation, 90 million adults were living with diabetes in the IDF South-East Asia Region. This figure is estimated to increase to 152 million by 2045, and the 206 million adults living with diabetes in the IDF Western Pacific Region, are estimated to increase to 260 million by 2045. Diabetes is associated with many health complications. Patients with diabetes require many corrections throughout the day for maintaining normal blood glucose levels, such as oral anti-diabetic medication, insulin administration, or the ingestion of additional carbohydrates by monitoring their blood glucose levels.

According to the Ministry of Health and Family Welfare of the Government of India, out of all deaths in India, 60% were related to non-communicable diseases like diabetes, cardiovascular diseases, cancer, chronic respiratory diseases, etc. To prevent and control major NCDs, the National Program for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases, and Stroke (NPCDCS) has been launched. This program includes medical education, health awareness in schools, and urban planning for diabetes.

Owing to the rising rate of obesity, the growing genetic factors for type-2 diabetes, the increasing prevalence, and the aforementioned factors, it is likely that the market will continue to grow.

Biguanides Market, Growth Rate by Region, 2023-2028

Biguanides Industry Overview

The biguanides market is fragmented, with manufacturers like Takeda, Merck, Sanofi, GlaxoSmithKline, Bristol-Myers Squibb, Boehringer Ingelheim Pharmaceuticals, etc. having a global market presence, and the market is highly competitive due to generic drug manufacturers' presence.

Biguanides Market Leaders

  1. Bristol Myers Squibb

  2. Glenmark Pharmaceuticals

  3. Takeda

  4. Sanofi Aventis

  5. Merck and Co.

*Disclaimer: Major Players sorted in no particular order

Biguanides Market Concentration
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Biguanides Market News

  • February 2023: Zydus Lifesciences Limited received tentative approval from the USFDA for Invokamet tablets (canagliflozin and metformin hydrochloride combination). Canagliflozin and metformin combination products are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are not adequately controlled on a regimen containing metformin or canagliflozin or in patients already being treated with both canagliflozin and metformin.
  • February 2022: Merck announced in a European work sharing procedure (WSP) an extension to the label for metformin products in the European Union: Glucophage (metformin hydrochloride immediate release), Glucophage XR (metformin HCL extended release), and Stagid (metformin embonate immediate release) for use throughout pregnancy. The approval was granted based on Merck's own safety cohort study, CLUE, and a large body of published evidence.

Biguanides Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
  • 4.3 Market Restraints
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Bargaining Power of Suppliers
    • 4.4.2 Bargaining Power of Consumers
    • 4.4.3 Threat of New Entrants
    • 4.4.4 Threat of Substitute Products and Services
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION

  • 5.1 Biguanide
  • 5.2 Geography
    • 5.2.1 North America
    • 5.2.1.1 United States
    • 5.2.1.2 Canada
    • 5.2.1.3 Rest of North America
    • 5.2.2 Europe
    • 5.2.2.1 Germany
    • 5.2.2.2 Spain
    • 5.2.2.3 Italy
    • 5.2.2.4 France
    • 5.2.2.5 United Kingdom
    • 5.2.2.6 Russia
    • 5.2.2.7 Rest of Europe
    • 5.2.3 Asia-Pacific
    • 5.2.3.1 Japan
    • 5.2.3.2 China
    • 5.2.3.3 Australia
    • 5.2.3.4 India
    • 5.2.3.5 South Korea
    • 5.2.3.6 Malaysia
    • 5.2.3.7 Indonesia
    • 5.2.3.8 Thailand
    • 5.2.3.9 Philippines
    • 5.2.3.10 Vietnam
    • 5.2.3.11 Rest of Asia-Pacific
    • 5.2.4 Latin America
    • 5.2.4.1 Brazil
    • 5.2.4.2 Mexico
    • 5.2.4.3 Rest of Latin America
    • 5.2.5 Middle East and Africa
    • 5.2.5.1 South Africa
    • 5.2.5.2 Saudi Arabia
    • 5.2.5.3 Oman
    • 5.2.5.4 Egypt
    • 5.2.5.5 Iran
    • 5.2.5.6 Rest of Middle East and Africa

6. MARKET INDICATORS

  • 6.1 Type-1 Diabetes Population
  • 6.2 Type-2 Diabetes Population

7. COMPETITIVE LANDSCAPE

  • 7.1 COMPANY PROFILES
    • 7.1.1 Teva
    • 7.1.2 Merck
    • 7.1.3 Takeda
    • 7.1.4 GlaxoSmithKline
    • 7.1.5 Sanofi
    • 7.1.6 Boehringer Ingelheim
    • 7.1.7 Glenmark
    • 7.1.8 Zydus
    • 7.1.9 Bristol-Myers Squibb
  • *List Not Exhaustive
  • 7.2 MARKET SHARE ANALYSIS
    • 7.2.1 Merck
    • 7.2.2 Takeda
    • 7.2.3 Sanofi
    • 7.2.4 Other Market Share Analyses

8. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
*The report covers a segment-wise breakdown (Value and Volume) for all the countries covered under Table of Contents **Competitive Landscape covers- Business Overview, Financials, Products and Strategies, and Recent Developments
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Biguanides Industry Segmentation

Biguanides are a class of diabetes medications that are used for people with type-2 diabetes. The biguanide market is segmented by geography. The report offers the value (in USD) and volume (in units) for the above segments.

Geography North America United States
Canada
Rest of North America
Geography Europe Germany
Spain
Italy
France
United Kingdom
Russia
Rest of Europe
Geography Asia-Pacific Japan
China
Australia
India
South Korea
Malaysia
Indonesia
Thailand
Philippines
Vietnam
Rest of Asia-Pacific
Geography Latin America Brazil
Mexico
Rest of Latin America
Geography Middle East and Africa South Africa
Saudi Arabia
Oman
Egypt
Iran
Rest of Middle East and Africa
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Biguanides Market Research FAQs

The Biguanides Market size is expected to reach USD 5.20 billion in 2024 and grow at a CAGR of 2.07% to reach USD 5.76 billion by 2029.

In 2024, the Biguanides Market size is expected to reach USD 5.20 billion.

Bristol Myers Squibb, Glenmark Pharmaceuticals, Takeda, Sanofi Aventis and Merck and Co. are the major companies operating in the Biguanides Market.

Middle East and Africa is estimated to grow at the highest CAGR over the forecast period (2024-2029).

In 2024, the Asia-Pacific accounts for the largest market share in Biguanides Market.

In 2023, the Biguanides Market size was estimated at USD 5.09 billion. The report covers the Biguanides Market historical market size for years: 2018, 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Biguanides Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.

Biguanides Industry Report

Statistics for the 2024 Biguanides market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Biguanides analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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Biguanides Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)