Cell And Gene Therapy Contract Development And Manufacturing Organization Market Size (2024 - 2029)

Cell And Gene Therapy Contract Development And Manufacturing Organization Market Analysis

The Cell And Gene Therapy Contract Development And Manufacturing Organization Market size is estimated at USD 3.18 billion in 2024, and is expected to reach USD 6.90 billion by 2028, growing at a CAGR of 16.73% during the forecast period (2024-2028).

Many clinical trials for cell and gene therapies experienced delays due to disruptions in patient recruitment, monitoring, and regulatory processes caused by the pandemic. Moreover, the urgency to combat the pandemic has led to increased investment and focus on biopharmaceuticals, including cell and gene therapies, and this has accelerated research and development efforts in the field. Many CDMOs with expertise in cell and gene therapy manufacturing have pivoted their resources and capabilities to support vaccine production. For instance, in November 2022, SK Bioscience, a CDMO company, extended its partnership with Novavax for the COVID-19 vaccine and has also secured additional CMO and CDMO partners. The increased demand for COVID-19 vaccines has led to more outsourced manufacturing agreements for CDMOs, which has contributed to the market's growth.

The major factors driving the growth of the market are the increasing burden of chronic diseases, high investment in the development of cell and gene therapy, and the rise in preclinical and clinical activities around viral vector-based gene therapy.

Cell and gene therapy is effective in the management of several chronic diseases, including cancer, cardiac diseases, neurological, and infectious diseases. Pharmaceutical companies are also extensively engaged in developing novel therapeutics for these diseases, which is likely to increase the demand for cell and gene therapy CDMO market. The increasing burden of chronic diseases is creating demand for advanced therapies, thereby boosting market growth. For instance, according to the Centers for Disease Control and Prevention (CDC) data of 2023, each year in the United States, about 6,000 babies are born with Down syndrome, which is about 1 in every 700 babies born. Moreover, according to the World Heart Federation data published in May 2022, cardiovascular disease, including heart disease and stroke, is the most common non-communicable disease globally, responsible for nearly 18.6 million deaths, of which more than three-quarters occur in low- and middle-income countries. Hence, the high burden of chronic diseases such as Down syndrome and communicable diseases that require cell and gene therapy is projected to contribute to the market growth over the forecast period.

The growing collaboration and partnerships between biopharmaceutical companies and CDMOs are anticipated to provide an opportunity for market players in the growth of the cell and gene therapy CDMO services market over the forecast period. For instance, in May 2023, AGC Biologics announced the launch of its BravoAAV and ProntoLVV viral vector platforms offering flexible and accelerated vector development and manufacturing for cell and gene therapy programs. AGC Biologics' new platforms capitalize on their extensive expertise in lentiviral vector (LVV) and adeno-associated viral vector (AAV) development, manufacturing, and analytical experience spanning three decades. These platforms provide rapid, effective, and consistent clinical and commercial GMP production and release capabilities. Additionally, in October 2022, ABL, a CDMO, and RD-Biotech signed a strategic partnership to cover cell and gene therapy GMP manufacturing. This collaboration is likely to bring together RD-Biotech’s plasmid DNA (pDNA) GMP manufacturing services with ABL’s viral vector GMP manufacturing.

Hence, the growing burden of chronic diseases and strategic activities undertaken by the market players are expected to boost the market over the forecast period. However, complex manufacturing processes, regulatory challenges, and the high cost of research are expected to boost the market over the forecast period.

Cell And Gene Therapy Contract Development And Manufacturing Organization Industry Segmentation

As per the scope of the report, cell and gene therapy contract development and manufacturing organization (CDMO) services refer to specialized offerings provided by companies that support the development, production, and testing of cell and gene therapies. These therapies involve the use of living cells or genetic material to treat diseases. The cell and gene therapy contract development and manufacturing organization market is segmented by product (cell therapy and gene therapy), source (pre-clinical, clinical, and commercial), indication (oncology, cardiovascular disease, infectious disease, genetic disorders, neurological disorders, and other indications), and geography (North America, Europe, Asia-Pacific, the Middle East and Africa, and South America). The report also covers the estimated market sizes and trends for 17 countries across major regions globally.

The report offers the value (in USD) for the above segments.