Market Trends of Global Cholera Vaccines Industry
This section covers the major market trends shaping the Cholera Vaccines Market according to our research experts:
Whole-cell V. cholerae O1 with a Recombinant B-subunit Segment is Expected to Witness Significant Growth Over the Forecast Period.
Whole-cell V. cholerae O1 with a recombinant B-subunit segment captures the largest market share. This cholera vaccine containing a combination of recombinant B-subunit and killed the whole cell V. cholerae O1 has been marketed for the last three decades. This vaccine is observed to provide 80-90% protection for six months, post-immunization, and in all cases of immunization of vaccines aged more than two years. In addition to this, these vaccines show around 50% of protection even after three years of immunization. The factors that are driving the growth of this segment are the high number of cholera cases recorded globally and the efficacy, and long-lasting post-immunization protections of the vaccine are expected to propel the segment's growth over the forecast period.
An article published by ACS News Service in February 2022 reported that the Dukoral vaccine contains a mixture of formalin- and heal-killed V cholera O1 bacteria, representing both the Ogawa and Inaba serotypes and the classical and EI Tor biotypes and a recombinantly produced cholera toxin B subunit. The trials of this vaccine were undertaken in 90,000 children and women in Bangladesh and showed an 85% protective efficacy against cholera during the first 4-6 months and 50-60% efficacy over a 3-year follow-up period after two or three vaccination. Thus, the high efficacy of this vaccine is expected to increase the demand, thereby driving the growth of this segment.
Additionally, the high number of cholera cases recorded globally is also expected to increase the demand for cholera vaccines. For instance, European Center for Disease Prevention and Control (ECDC) in 2022 reported 25.8 thousand cholera cases in Pakistan, followed by 46.2 thousand cholera cases recorded in Bangladesh in the year 2022. Thus, a high number of cholera cases is expected to drive the growth of this segment.
Thus, the high number of cholera cases recorded globally and the efficacy and long-lasting post-immunization protections of the vaccine are expected to drive the growth of this segment.
North America is Expected to Witness Significant Growth Over the Forecast Period.
North America consists of three countries, the United States, Canada, and Mexico. The region is expected to witness significant growth over the forecast period owing to the presence of advanced research and the major players that is leading to the development of a novel cholera vaccine, a high number of cholera cases recorded globally, and rising government initiatives.
The high number of cholera cases recorded in Mexico region is expected to increase the demand for cholera vaccines, thereby driving the growth of the market in the region. For instance, in October 2022, Mexico Health Ministry recorded 45,000 cholera cases in the country from January 2022 - September 2022. Thus, the high number of cholera cases is driving the growth of the studied market in the region.
Additionally, the rising government initiatives to control cholera are expected to drive the growth of the studied market in the region. For instance, in December 2021, Health Canada updated the guidelines on the prevention and control of infectious diseases like cholera. These initiatives are expected to increase awareness among the people in the country and thus increase the demand for cholera vaccines, thereby driving the growth of the studied market.
Furthermore, ongoing clinical studies are also driving the growth of the market. For instance, an article published by the journal Vaccine in May 2022 reported that a double-blind, randomized, placebo-controlled, phase I study conducted in the United States in which oral immunization with 6-g doses of MucoRice- cholera toxin (CTB) induced cross-reactive antigen-specific antibodies against CTB and heat-labile toxin B subunit (LTB) in serum and saliva in was conducted in healthy men and women. The study was successful, and this dose was safe and adequate to control cholera. Thus, such clinical studies for vaccine development in the country are expected to drive the growth of the studied market.
Thus, the high number of cholera cases recorded globally, rising government initiatives, and rising clinical studies are driving the growth of the studied market in the region.
