Market Size of CRISPR And CRISPR-associated (Cas) Genes Industry
Study Period | 2019 - 2029 |
Base Year For Estimation | 2023 |
Forecast Data Period | 2024 - 2029 |
CAGR | 15.67 % |
Fastest Growing Market | Asia Pacific |
Largest Market | North America |
Major Players*Disclaimer: Major Players sorted in no particular order |
Need a report that reflects how COVID-19 has impacted this market and its growth?
CRISPR and CAS Genes Market Analysis
The CRISPR and CRISPR-associated (Cas) genes market is expected to register a CAGR of 15.67% over the forecast period.
- The COVID-19 pandemic had a significant impact on the market due to an increase in demand for COVID-19 diagnostic tests since the CRISPR-Cas-based methods diagnose the SARS-CoV-2 infections within an hour. As per the April 2022 update from Duke Health, a study conducted by the researchers demonstrated that CRISPR technology represents a unique strategy for controlling SARS-CoV-2 infection and should be pursued as a potential approach for treating COVID.
- The CRISPR/Cas13 delivered intravenously through a lipid nanoparticle diminished CTSL in the animals' lungs, effectively and safely blocking the SARS-CoV-2 virus from entering cells and infecting the host. Thus, studies such as these are expected to have a positive effect on the market for CRISPR and CRISPR-associated (Cas) Genes. Since the restrictions of COVID-19 is relaxed, the market is anticipated to witness growth in the coming years due to the increase in research activities involving CRISPR and CRISPR-associated (Cas) Genes.
- Factors attributing to the growth of the market include increasing investment by biotechnology companies for novel therapeutics, a rise in genomics research and development activities, and a high burden of cancer and other diseases. For instance, in January 2021, Pfizer Inc. invested a total of USD 120 million in four clinical-stage biotech companies as part of the Pfizer Breakthrough Growth Initiative (PBGI). Through PBGI, Pfizer invested up to USD 500 million in biotechnology companies, providing funding and access to Pfizer's scientific expertise to help ensure the continuity of promising clinical development programs of potential future strategic interest to Pfizer. Hence, such investment by the key players is expected to increase the development of CRISPR and CRISPR-associated (Cas) genes and thereby drive market growth over the forecast period.
- Furthermore, the rise in genomics research and development activities that demonstrate the efficiency of CRISPR technologies is likely to boost market growth over the forecast period. For instance, in May 2022, Vertex and CRISPR Therapeutics presented new clinical data on investigational CRISPR/Cas9 Gene-Editing Therapy CTX001 for severe hemoglobinopathies at the annual European Hematology Association Virtual Congress. CTX001 is being investigated in two ongoing clinical trials as a potential one-time curative therapy for patients suffering from TDT and severe SCD.
- Moreover, a high burden of cancer and other diseases is boosting market growth since CRISPR technology has been found to help identify the mutations in several cancers. For instance, as per the American Cancer Society, the estimated number of people diagnosed with cancer in 2022 was 1.9 million in the United States.
- Additionally, in the article published in November 2022 in Nature Journal, researchers can use CRISPR gene editing to change immune cells so that they will recognize altered proteins unique to a person's tumors. Then, those cells can be safely released into the body to locate and eliminate their target. Hence, such personalized treatment options provided by the CRISPR technologies for chronic disease like cancer is expected to drive the market growth over the forecast period.
- Hence, due to the rising investment by biotechnology companies for novel therapeutics and the increase in genomics research and development activities, the market studied is anticipated to witness growth over the forecast period. However, off-target effects associated with the implementation of CRISPR and high cost and ethical concerns associated with CRISPR technology are expected to restrain the market growth over the forecast period.
CRISPR and CAS Genes Industry Segmentation
As per the scope of the report, clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) Genes market, CRISPR-Cas9, which is an acronym for clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9 is a microbial adaptive immune system against viruses and plasmids, that gives scientists the ability to change an organism's DNA (genome editing).
The CRISPR and CRISPR-associated (Cas) genes market is segmented by product (vector-based cas and DNA-free cas), application (genome engineering, disease models, functional genomics, and others), and geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report also covers the estimated market sizes and trends for 17 countries across major regions globally.
The report offers the value (in USD) for the above segments.
By Product | |
Vector-based Cas | |
DNA-free Cas |
By Application | |
Genome Engineering | |
Disease Models | |
Functional Genomics | |
Other Applications |
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CRISPR And CRISPR-associated (Cas) Genes Market Size Summary
The CRISPR and CRISPR-associated (Cas) genes market is poised for significant growth, driven by increasing investments in biotechnology and a surge in genomics research and development activities. The market has experienced a boost due to the COVID-19 pandemic, which highlighted the rapid diagnostic capabilities of CRISPR-Cas-based methods. As research activities expand, the market is expected to benefit from advancements in novel therapeutics and personalized medicine, particularly in cancer treatment. The technology's ability to identify mutations and modify immune cells for targeted cancer therapies is anticipated to further propel market expansion. However, challenges such as off-target effects, high costs, and ethical concerns may pose constraints to market growth.
North America is projected to maintain a substantial share of the CRISPR and CRISPR-associated (Cas) genes market, supported by a robust healthcare infrastructure, significant research funding, and favorable government initiatives. The region's market growth is bolstered by strategic collaborations and investments in biomanufacturing and biotechnology. Key players in the market, including OriGene Technologies, Inc., Thermo Fisher Scientific, and CRISPR Therapeutics, are actively engaging in strategic alliances and product innovations to strengthen their market positions. The ongoing clinical studies and advancements in gene-editing therapies, such as those targeting type 1 diabetes, underscore the region's leadership in the CRISPR market.
CRISPR And CRISPR-associated (Cas) Genes Market Size - Table of Contents
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1. MARKET DYNAMICS
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1.1 Market Overview
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1.2 Market Drivers
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1.2.1 Increasing Investment by Biotechnology Companies for Novel Therapeutics
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1.2.2 Increasing Genomics Research and Development Activities and Funding
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1.2.3 High Burden of Cancer and Other Diseases
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1.3 Market Restraints
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1.3.1 Off-target Effects Associated with the Implementation of CRISPR
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1.3.2 High Cost and Ethical Concerns Associated with CRISPR Technology
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1.4 Porter's Five Forces Analysis
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1.4.1 Threat of New Entrants
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1.4.2 Bargaining Power of Buyers/Consumers
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1.4.3 Bargaining Power of Suppliers
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1.4.4 Threat of Substitute Products
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1.4.5 Intensity of Competitive Rivalry
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2. MARKET SEGMENTATION (Market Size by Value - USD)
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2.1 By Product
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2.1.1 Vector-based Cas
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2.1.2 DNA-free Cas
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2.2 By Application
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2.2.1 Genome Engineering
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2.2.2 Disease Models
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2.2.3 Functional Genomics
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2.2.4 Other Applications
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2.3 Geography
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2.3.1 North America
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2.3.1.1 United States
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2.3.1.2 Canada
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2.3.1.3 Mexico
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2.3.2 Europe
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2.3.2.1 Germany
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2.3.2.2 United Kingdom
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2.3.2.3 France
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2.3.2.4 Italy
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2.3.2.5 Spain
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2.3.2.6 Rest of Europe
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2.3.3 Asia-Pacific
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2.3.3.1 China
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2.3.3.2 Japan
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2.3.3.3 India
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2.3.3.4 Australia
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2.3.3.5 South Korea
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2.3.3.6 Rest of Asia-Pacific
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2.3.4 Middle East and Africa
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2.3.4.1 GCC
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2.3.4.2 South Africa
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2.3.4.3 Rest of Middle East and Africa
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2.3.5 South America
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2.3.5.1 Brazil
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2.3.5.2 Argentina
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2.3.5.3 Rest of South America
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CRISPR And CRISPR-associated (Cas) Genes Market Size FAQs
What is the current CRISPR And CRISPR-associated (Cas) Genes Market size?
The CRISPR And CRISPR-associated (Cas) Genes Market is projected to register a CAGR of 15.67% during the forecast period (2024-2029)
Who are the key players in CRISPR And CRISPR-associated (Cas) Genes Market?
OriGene Technologies, Inc., Thermo Fisher Scientific, Takara Bio Inc, Addgene and PerkinElmer Inc. (Horizon Discovery Ltd.) are the major companies operating in the CRISPR And CRISPR-associated (Cas) Genes Market.