Market Trends of Gemcitabine Hydrochloride Industry
This section covers the major market trends shaping the Gemcitabine Hydrochloride Market according to our research experts:
Lung Cancer is Expected to Witness Significant Growth Over the Forecast Period
The lung cancer segment is expected to hold a significant share in the growth of the market owing to the high prevalence of lung cancer cases and rising demand for the growth of effective treatment for lung cancer.
For instance, in the Lung Cancer Foundation data published in 2022, an estimated 236,74 people were diagnosed with lung cancer in the United States, 2022. Additionally, the NCBI article published in January 2022 mentioned that the incidence of lung cancer among the non-smoker female population was 17.1 per 100,000 in 2022. The article also mentioned that non-smoker Chinese American females and the highest rate of cancer which was 22.8 per 100,000 in 2021. Such increasing incidence of lung cancer among the global population is expected to drive the demand for effective treatment, thereby driving segment growth.
Likewise, the research studies proving the efficacy of gemcitabine in the treatment of lung cancer are also expected to drive segment growth. For instance, according to an article published in the National Library of Medicine in August 2021, combination therapy of gemcitabine with a platinum agent is a highly effective treatment among the platinum doublet regimens. It is promising as a treatment for advanced squamous cell lung carcinoma. Thus, such research activities will lead to verticle growth in the coming future. On the other hand, the rising product developments and clinical trials by various market players are also expected to contribute to the market's growth. For instance, in August 2022, Ipsen Announced results from the phase III resilient trial evaluating Onivyde in second-line monotherapy for small lung cancer. Onivyde is approved in combination with fluorouracil and leucovorin for the treatment of patients following gemcitabine-based therapy.
Thus, the high prevalence of lung cancer, research and development associated with lung cancer, and lower side effects of gemcitabine are expected to boost the growth of the studied segment over the forecast period.
North America is Expected to Hold Significant Share in the Market over the Forecast Period
North America is expected to hold a major market share in the global gemcitabine hydrochloride market due to the increasing burden of cancer diseases and product advancements. The low cost of generic gemcitabine hydrochloride and reformulation strategies adopted by companies are among the other driving factor for market growth.
For instance, according to the American Cancer Society Inc., data published in 2022, in 2021, there were an estimated 1.9 million new cancer cases diagnosed in the United States. In addition, according to the Public Health Agency of Canada data published in October 2021, approximately 2 in 5 Canadians were diagnosed with Cancer in their lifetime. In 2021, an estimated 229,000 Canadians were diagnosed with Cancer. The report also mentioned that lung, breast, colorectal, and prostate cancers were expected to remain the most commonly diagnosed cancers, accounting for nearly 46% of all cancer diagnoses in 2021. Such a high prevalence of cancers in North American countries is expected to contribute to the market's growth.
In June 2022, Fujifilm announced that it had begun implementation of a phase 2 study in the United States to evaluate the safety, tolerability, and preliminary efficacy of FF-10832, a liposomal drug candidate, in combination therapy with Merck & Co Keytruda (pembrolizumab) for patients with advanced solid tumors. FF-10832 is a liposomal formulation that encapsulates gemcitabine, an approved anti-cancer agent indicated for the treatment of a variety of solid tumors.
Additionally, in April 2022, Tiziana Life Sciences announced filing an investigational new drug application and initiating a Phase 2 trial in KRAS (Kirsten rat sarcoma viral) + NSCLC (Non-small cell lung cancer) patients with a combination of milciclib + gemcitabine. The positive outcome of such clinical trials may lead to new treatment options, thereby increasing regional growth.
