Global Minimal Residual Disease Market Trends

Statistics for the 2023 & 2024 Global Minimal Residual Disease market trends, created by Mordor Intelligence™ Industry Reports. Global Minimal Residual Disease trend report includes a market forecast to 2029 and historical overview. Get a sample of this industry trends analysis as a free report PDF download.

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Market Trends of Global Minimal Residual Disease Industry

This section covers the major market trends shaping the Minimal Residual Disease Market according to our research experts:

Next Generation Sequencing (NGS) Segment Expects to Register a Highest CAGR in the Forecast Period

Next-generation sequencing is a technology used to determine the sequence of DNA or RNA to study the genetic variations associated with the disease. It is also called as massively-parallel sequencing as it enables the sequencing to determine the sequencing of many DNA at a particular time.

The factors propelling the growth of next-generation sequencing technology are increasing incidences of cancer globally, rising demand for next-generation sequencing services and applications in drug development, clinical procedures, precision medicines, and adoption of the latest technology established for next-generation sequencing.

Recently, new assays, including next-generation sequencing, were developed to monitor minimal residual disease more precisely in the patients. Next-Generation Sequencing offers greater sensitivity than conventionally employed morphologic and cytogenetic tests. According to an article published by the Journal of Molecular Diagnostics in January 2020, titled 'A New Next-Generation Sequencing Strategy for the Simultaneous Analysis of Mutations and Chromosomal Rearrangements at DNA Level in Acute Myeloid Leukemia Patients' it has been found that the next-generation sequencing offers the promise of detecting all genomic lesions in a single run. In addition, next-generation sequencing applies to every newly diagnosed acute myeloid leukemia because of the frequent prevalence of multiple molecular aberrations among patients.

The introduction of various error-corrected next-generation methodologies has made the detection of minimal residual diseases easy. Molecular barcoding has recently been used to develop several error-corrected next-generation sequencing approaches based on barcoding the individual DNA molecules used for next-generation sequencing library creation. According to an article published by the National Center for Biotechnology Information in June 2021, titled "Minimal Residual Disease Monitoring with Next-Generation Sequencing," it has been found that next-generation sequencing has the potential to reduce the prevalence of undiagnosed minimal residual diseases, allowing for early management, which is critical for Acute lymphocytic leukemia (ALL) patient survival.

Moreover, the companies' investment in research and development activities, adoption of advanced technology, and increasing their focus on developing assays to assess minimal residual disease are likely to increase the growth of next-generation sequencing over the forecast period. For instance, in January 2020, Adaptive Biotechnologies collaborated with GlaxoSmithKline to use its clonoSEQ Assay to assess minimal residual disease (MRD) in GSK's portfolio of hematology products.

Minimal Residual Disease Market Trends

North America is Expected to Have the Significant Market Share during the Forecast Period

The increasing incidences of cancer, rising demand for next-generation and polymerase chain reaction techniques for detecting minimal residual diseases, adoption of the latest technology, and established research infrastructure for proteomics, genomics, and oncology are the factors propelling the growth of the market in the North American region.

The increasing incidences and prevalence of hematological cancers in the United States have increased the risk of people having residual cancerous cells, which is likely to increase the demand for minimal residual disease market. According to the statistics published by the American Cancer Society 2022, 34,470 new cases of multiple myeloma in the United States in 2022. In addition, as per the same source, about 6,660 new cases of acute lymphocytic leukemia (ALL) in 2022. As per the statistics published by the Leukemia and Lymphoma Society, in 2021, 90,390 new lymphoma cases were expected to be diagnosed in patients in the United States, of which 8,830 cases would be of Hodgkin lymphoma and 81,560 cases of non-Hodgkin lymphoma.

Moreover, the increasing focus of the companies on developing treatments and tests for detecting minimal residual disease is also contributing to the market's growth. For instance, in February 2022, Invitae launched a study to generate real-world data on personalized minimal residual disease tests across various tumor types. Similarly, in April 2020, Inivata launched an assay, RaDaR, to detect and monitor residual disease and recurrence in the plasma samples of patients previously diagnosed with cancer. The RaDaR assay is built on Inivata's proven InVision liquid biopsy platform technology, a next-generation sequencing platform that incorporates built-in controls and error correction for highly sensitive and specific variant detection.

Minimal Residual Disease Market Analysis

Minimal Residual Disease Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)