Nucleic Acid Isolation & Purification Market Size
| Study Period | 2019 - 2029 |
| Market Size (2024) | USD 4.45 Billion |
| Market Size (2029) | USD 6.81 Billion |
| CAGR (2024 - 2029) | 8.89 % |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Need a report that reflects how COVID-19 has impacted this market and its growth?
Nucleic Acid Isolation & Purification Market Analysis
The Nucleic Acid Isolation And Purification Market size is estimated at USD 4.45 billion in 2024, and is expected to reach USD 6.81 billion by 2029, growing at a CAGR of 8.89% during the forecast period (2024-2029).
COVID-19 significantly impacted the growth of the market during the pandemic period. This was mainly due to the significant increase in testing and drug research about the disease. During the pandemic, the need for nucleic acid and purification grew due to research in this field to better understand the dynamics of the SARS-CoV-2 virus and COVID-19 infection. For instance, as per the NCBI article published in November 2021, a direct capture method for the purification and detection of viral nucleic acid enabled epidemiological surveillance of SARS-CoV-2. Also, the usage of nucleic acid and purification in the diagnostic assays and molecular testing of COVID-19, along with vaccine development, played a vital role in the market's growth. In addition, the rising research activities due to the emergence of mutant strains of COVID-19 during the post-pandemic period are expected to contribute to the market growth over the forecast period.
Factors such as an increase in demand for sequencing platforms in clinical diagnostics, a rise in genomics research, and growth in funding for research and development in molecular biology are anticipated to drive the market growth over the forecast period. For instance, PCR Biosystems offered grants for UK researchers worth EUR 10,000 (USD 10,591.08) for funding polymerase chain reaction (PCR) reagents to scientists working in human health, microbiology, plant sciences, environment, and sustainability, and other such research areas. Thus, research will likely require more nucleic acid extraction and isolation products, thereby driving market growth over the forecast period.
Furthermore, product launches and collaboration by the key players are anticipated to strengthen the competition in the market. For instance, in April 2022, Purigen Biosystems, Inc., a provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, launched the Ionic Cells to Pure DNA Kit. The new kit was optimized to allow users of the Ionic Purification System to extract increased yields of high-quality DNA from WBCs, peripheral blood mononuclear cells (PBMCs), and cultured or sorted cells. Furthermore, in November 2021, Bertin Bioreagent launched two kits to extract DNA and total RNA from animal tissues. These kits are part of a complete sample preparation workflow that starts with tissue homogenization using Precellys instruments. The Bertin Life Sciences R&D team validated their quality.
Hence, due to the rise in research activities, funding in the field of nucleic acid isolation and purification, and an increase in reagent product launches, the nucleic acid isolation and purification market is anticipated to witness growth over the forecast period. However, the increasing cost of automated instruments and the lack of skilled professionals are expected to restrain the market's growth over the forecast period.
Nucleic Acid Isolation & Purification Market Trends
The Equipment Segment is Expected to Hold a Major Market Share in the Nucleic Acid Isolation and Purification Market
The equipment segment of the market studied is growing at a good pace. There are significant advancements in the field of molecular diagnostics that have facilitated rapid and continuous advancements in nucleic acid isolation and purification technologies, driven by the new knowledge provided by the mapping of genetic risk factors behind many diseases, where lifestyle has an important role to play.
For procedures including sample preparation, gene expression, DNA/RNA analysis, and PCR, automated nucleic acid purification equipment extract and purify genomic and plasmid DNA from cells, tissue, and whole blood samples. There are systems that use sealed cartridges to solve compatibility and contamination concerns, as well as open and closed platforms. Magnetic bead-based methods and spin-column purification are two technologies for nucleic acid extraction and purification that provide quick, dependable nucleic acid recovery and purity while lowering human error and standardizing procedures.
The market is expanding as a result of the availability of cutting-edge technological products. For instance, QIAGEN's sample homogenization, automated DNA and RNA extraction, and automated RNA extraction solutions are effortlessly integrated into daily research and enable the transformation of biological samples into important molecular insights quickly. Additionally, over the past few decades, magnetic beads (particles) were created that could aid in overcoming the difficulties now present. They enable the quick and effective direct purification of the DNA/RNA from crude cell extracts using an appropriate buffer solution. Workflow is automated by the Aurora VERSA and ADNAP extraction systems, two generations of equipment that are based on the Magnetic Bead RNA/DNA Extraction technique.
Thus, the growth in laboratory automation may lead to the growth of the equipment segment of the market studied.
North America is Expected to Hold a Significant Share in the Market and Expected to do Same in the Forecast Period
North America is expected to witness growth in the nucleic acid isolation and purification market. This is due to various factors, such as a rise in research and development in the genomic field that requires nucleic acid isolation and purification procedures, an increase in demand for sequencing platforms in clinical diagnostics, and growth in funding for research and development in molecular biology. In June 2021, UCLA Health received a USD 4.8 million grant from the National Institutes of Health to develop methods that were likely to improve genetic risk estimates and polygenic risk scores for specific diseases in people from diverse populations and mixed ancestries.
Furthermore, in September 2021, Beckman Coulter Life Sciences launched the EMnetik System to semi-automate workflows while reducing the time required for a PCR cleanup. Built using electromagnets, EMnetik 24 and the accompanying EMnetik PCR Cleanup Kit and EMnetik Plasmid Purification Kit use magnetic bead-based technology to clean nucleic acids in a stationary device. The benchtop instrument can run 1-24 samples at a time. The streamlined cleanup process and semi-automation also helped eliminate potential errors.
Besides, the high prevalence of genetic disorders is contributing to market growth. For instance, according to the CDC data published in 2020, Hemophilia A affects 1 in 5,000 male births in the United States. Each year approximately 400 babies are born with hemophilia A. Such frequency of genetic disorders is expected to drive the demand for nucleic acid and purification for the effective diagnostics and development of effective treatment procedures.
Thus, due to the rise in research and development in the genomic field that requires nucleic acid isolation and purification procedures, along with the surge in product launches, North America is anticipated to witness a growth in the nucleic acid isolation and purification market over the forecast period.
Nucleic Acid Isolation & Purification Industry Overview
The nucleic acid isolation and purification market is fragmented in nature and consists of several major players. The competitive landscape includes an analysis of a few international and local companies that hold market shares and are well known. Major market players include Agilent Technologies, Bio-Rad Laboratories Inc., Danaher Corporation, F. Hoffmann-La Roche Ltd, GE Healthcare, Promega Corporation, Qiagen NV, and Thermo Fisher Scientific Inc., among others
Nucleic Acid Isolation & Purification Market Leaders
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Agilent Technologies
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Bio-Rad Laboratories Inc.
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Danaher Corporation
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GE Healthcare
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Thermo Fisher Scientific
*Disclaimer: Major Players sorted in no particular order
Nucleic Acid Isolation & Purification Market News
- April 2022: Purigen launched Ionic Cells to Pure DNA Low Input Kit for researchers working with limited biological samples. The simplified and automated 60-minute workflow delivers high-quality DNA for the rapid investigation of genetic abnormalities or examination of disease treatment effects.
- May 2022: Qiagen Inc. launched NeuMoDxHSV 1/2 Quant Assay for the quantification and differentiation of herpes simplex virus type 1 (HSV-1) DNA and/or herpes simplex virus type 2 (HSV-2) with approval from the European Commission. This assay's emergence allows the company to expand its product portfolio in laboratory testing, which ultimately helps the market growth owing to the innovative tests.
Nucleic Acid Isolation & Purification Market Report - Table of Contents
1. INTRODUCTION
- 1.1 Study Assumptions and Market Definition
- 1.2 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
- 4.1 Market Overview
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4.2 Market Drivers
- 4.2.1 Rapid Technological Advancements
- 4.2.2 Wide-range Applications of Nucleic Acid Testing in Diagnostics
- 4.2.3 Rise in the R&D Funding in Biotechnology
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4.3 Market Restraints
- 4.3.1 Lack of Skilled Professionals
- 4.3.2 Increasing Cost of Automated Instruments
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4.4 Porter Five Forces
- 4.4.1 Threat of New Entrants
- 4.4.2 Bargaining Power of Buyers/Consumers
- 4.4.3 Bargaining Power of Suppliers
- 4.4.4 Threat of Substitute Products
- 4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION (Market Size by Value - USD million)
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5.1 By Technology
- 5.1.1 Column-based Purification
- 5.1.2 Magnetic Bead-based Purification
- 5.1.3 Reagent-based Purification
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5.2 By Product
- 5.2.1 Kits and Reagents
- 5.2.2 Equipment
- 5.2.3 Other Products
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5.3 By Application
- 5.3.1 Total RNA Isolation and Purification
- 5.3.2 mRNA Isolation and Purification
- 5.3.3 microRNA Isolation and Purification
- 5.3.4 Plasmid DNA Isolation and Purification
- 5.3.5 Genomic DNA Isolation and Purification
- 5.3.6 Blood DNA Isolation and Purification
- 5.3.7 PCR Clean-up
- 5.3.8 Other Nucleic Acid Isolation and Purification Applications
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5.4 By End User
- 5.4.1 Hospitals
- 5.4.2 Academic and Research Institutes
- 5.4.3 Pharmaceutical/Biotechnology Industry
- 5.4.4 Other End Users
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5.5 Geography
- 5.5.1 North America
- 5.5.1.1 United States
- 5.5.1.2 Canada
- 5.5.1.3 Mexico
- 5.5.2 Europe
- 5.5.2.1 Germany
- 5.5.2.2 United Kingdom
- 5.5.2.3 France
- 5.5.2.4 Italy
- 5.5.2.5 Spain
- 5.5.2.6 Rest of Europe
- 5.5.3 Asia-Pacific
- 5.5.3.1 China
- 5.5.3.2 Japan
- 5.5.3.3 India
- 5.5.3.4 Australia
- 5.5.3.5 South Korea
- 5.5.3.6 Rest of Asia-Pacific
- 5.5.4 Middle East and Africa
- 5.5.4.1 GCC
- 5.5.4.2 South Africa
- 5.5.4.3 Rest of Middle East and Africa
- 5.5.5 South America
- 5.5.5.1 Brazil
- 5.5.5.2 Argentina
- 5.5.5.3 Rest of South America
6. COMPETITIVE LANDSCAPE
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6.1 Company Profiles
- 6.1.1 Agilent Technologies
- 6.1.2 Bio-Rad Laboratories Inc.
- 6.1.3 Thermo Fisher Scientific
- 6.1.4 BioVision Inc.
- 6.1.5 Danaher Corporation
- 6.1.6 F. Hoffmann-La Roche Ltd
- 6.1.7 GE Healthcare
- 6.1.8 Merck KGaA (Sigma-Aldrich Corporation)
- 6.1.9 Promega Corporation
- 6.1.10 Qiagen NV
- 6.1.11 Invitek Molecular
- 6.1.12 Analytik Jena AG
- *List Not Exhaustive
7. MARKET OPPORTUNITIES AND FUTURE TRENDS
** Subject To AvailablityNucleic Acid Isolation & Purification Industry Segmentation
As per the scope of the report, nucleic acid isolation is the process by which DNA and/or RNA are separated from proteins, membranes, and other cellular material, and purification removes as much of the additional lipids and proteins from the sample as possible. Nucleic Acids are the key component for many of today's molecular testing methods; therefore, the quality of the isolation step in the process is very important. The Nucleic Acid Isolation and Purification Market are segmented by Technology (Column-based Purification, Magnetic Bead-based Purification, and Reagent-based Purification), Product (Kits and Reagents, Equipment, and Other Products), Application (Total RNA Isolation and Purification, mRNA Isolation and Purification, microRNA Isolation and Purification and Purification and Plasmid DNA Isolation and Purification, Genomic DNA Isolation and Purification, Blood DNA Isolation and Purification, PCR Clean-up, Other Nucleic Acid Isolation, and Purification Applications), End User (Hospitals, Academic and Research Institutes, Pharmaceutical/Biotechnology Industry, and Other End Users), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions globally. The report offers the value (in USD million) for the above segments.
| By Technology | Column-based Purification | |
| Magnetic Bead-based Purification | ||
| Reagent-based Purification | ||
| By Product | Kits and Reagents | |
| Equipment | ||
| Other Products | ||
| By Application | Total RNA Isolation and Purification | |
| mRNA Isolation and Purification | ||
| microRNA Isolation and Purification | ||
| Plasmid DNA Isolation and Purification | ||
| Genomic DNA Isolation and Purification | ||
| Blood DNA Isolation and Purification | ||
| PCR Clean-up | ||
| Other Nucleic Acid Isolation and Purification Applications | ||
| By End User | Hospitals | |
| Academic and Research Institutes | ||
| Pharmaceutical/Biotechnology Industry | ||
| Other End Users | ||
| Geography | North America | United States |
| Canada | ||
| Mexico | ||
| Geography | Europe | Germany |
| United Kingdom | ||
| France | ||
| Italy | ||
| Spain | ||
| Rest of Europe | ||
| Geography | Asia-Pacific | China |
| Japan | ||
| India | ||
| Australia | ||
| South Korea | ||
| Rest of Asia-Pacific | ||
| Geography | Middle East and Africa | GCC |
| South Africa | ||
| Rest of Middle East and Africa | ||
| Geography | South America | Brazil |
| Argentina | ||
| Rest of South America |
Nucleic Acid Isolation & Purification Market Research FAQs
How big is the Nucleic Acid Isolation And Purification Market?
The Nucleic Acid Isolation And Purification Market size is expected to reach USD 4.45 billion in 2024 and grow at a CAGR of 8.89% to reach USD 6.81 billion by 2029.
What is the current Nucleic Acid Isolation And Purification Market size?
In 2024, the Nucleic Acid Isolation And Purification Market size is expected to reach USD 4.45 billion.
Who are the key players in Nucleic Acid Isolation And Purification Market?
Agilent Technologies, Bio-Rad Laboratories Inc., Danaher Corporation, GE Healthcare and Thermo Fisher Scientific are the major companies operating in the Nucleic Acid Isolation And Purification Market.
Which is the fastest growing region in Nucleic Acid Isolation And Purification Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).
Which region has the biggest share in Nucleic Acid Isolation And Purification Market?
In 2024, the North America accounts for the largest market share in Nucleic Acid Isolation And Purification Market.
What years does this Nucleic Acid Isolation And Purification Market cover, and what was the market size in 2023?
In 2023, the Nucleic Acid Isolation And Purification Market size was estimated at USD 4.05 billion. The report covers the Nucleic Acid Isolation And Purification Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Nucleic Acid Isolation And Purification Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.
Nucleic Acid Isolation and Purification Industry Report
Statistics for the 2024 Nucleic Acid Isolation and Purification market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Nucleic Acid Isolation and Purification analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.
