Global Protein Expression Market Size (2024 - 2029)

The protein expression market is projected to experience significant growth, driven by increased research and development activities in the pharmaceutical sector and advancements in the biologics market. The market's expansion is supported by the rising demand for biologics and the opportunities presented by proteomics, which are crucial for developing therapeutic and preventive strategies. Despite the market's attractiveness due to the adoption of biotechnology and genetic engineering, challenges such as high costs and limitations in post-translational modification systems may hinder growth.

Market Size of Global Protein Expression Industry

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Protein Expression Market Summary
Study Period 2019 - 2029
Market Size (2024) USD 2.88 Billion
Market Size (2029) USD 4.29 Billion
CAGR (2024 - 2029) 8.23 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Protein Expression Market Major Players

*Disclaimer: Major Players sorted in no particular order

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Protein Expression Market Analysis

The Global Protein Expression Market size is estimated at USD 2.88 billion in 2024, and is expected to reach USD 4.29 billion by 2029, growing at a CAGR of 8.23% during the forecast period (2024-2029).

The market has a slightly positive impact due to the pandemic. The development of therapeutic and preventive strategies requires an accurate understanding of the role that proteins play in the SARS-CoV-2 infection process and progression of COVID-19. The vast field of proteomics is well equipped with the technologies needed to help in facing this challenge. In an article published in October 2020 in the Journal of Proteins and Proteomics, researchers have highlighted that the developments in proteome technologies will not only accelerate progress in addressing the coronavirus pandemics but could also prove invaluable in tackling the current COVID-19 crisis.

The propelling factors for the growth of the protein expression market include the rise in the R&D activity in the pharmaceutical sector, opportunities in the field of proteomics, and advancements in the biologics market set to boost the market growth and the increasing incidences of chronic diseases. As per the World Health Organization, the major chronic diseases such as cardiovascular diseases (CVD), cancer, chronic obstructive pulmonary disease, and Type 2 diabetes are estimated to account for 73% of all deaths and 60% of the global burden of diseases in 2020.

Biologics have played a crucial role in the treatment process of many health issues. The success of Humira, a drug for the treatment of rheumatoid arthritis, has been an encouraging factor for many drug makers to continue working in the pathway of biologics. The growing demand for biologicals increases the prospects of its manufacturing using the protein expression systems, thus, boosting the market growth.

In addition, biotechnology-based organizations have also created a big opportunity for the protein expression market growth by developing novel therapeutics with minimal side effects. The increasing research intensity in the pharmaceutical sector is adding up to the opportunities for growth by technological advancement and product launch. For instance, in October 2020, Merck launched the Virus Express Lentiviral Production Platform, which can reduce process development time by approximately 40%.

Therefore, at present, the protein expression market is a highly attractive and profitable market due to the increasing adoption of biotechnology as well as genetic engineering in the pharmaceutical industry and medical science. However, the high cost of protein expression systems and lack of effective systems for post-translational modifications are expected to restrain the market growth over the forecast period.

Protein Expression Industry Segmentation

As per the scope of the report, protein expression is the way in which proteins are modified, synthesized, and regulated in living organisms. The term is applicable to either the object of study or the laboratory techniques required to manufacture proteins. Proteins are regulated and synthesized depending upon the functional need in the host cell. The translation, transcription, and post-translational modifications are the three processes involved in protein expression. The protein expression market is segmented by product (reagent and kits, service, and other products), application (therapeutic, industrial, and research), end user (academia, biotechnology and pharmaceuticals companies, and contract research organizations (CROs)), and geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The report offers the value (in USD million) for the above segments.

By Product
Reagents and Kits
Cell-free Expression
Bacterial Expression
Yeast Expression
Algal Expression
Insect Expression
Mammalian Expression
Other Expression Systems
Service
Other Products
By Application
Therapeutic
Industrial
Research
By End User
Academia
Biotechnology and Pharmaceuticals Companies
Contract Research Organizations (CROs)
By Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle-East and Africa
GCC
South Africa
Rest of Middle-East and Africa
South America
Brazil
Argentina
Rest of South America
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Global Protein Expression Market Size Summary

The protein expression market is poised for significant growth, driven by advancements in biotechnology and increasing research activities in the pharmaceutical sector. The market's expansion is supported by the rising demand for biologics and the development of novel therapeutics with minimal side effects. The COVID-19 pandemic has further highlighted the importance of proteomics, as understanding protein roles has been crucial in developing therapeutic and preventive strategies. The market benefits from the growing adoption of cell-free protein expression systems, which offer advantages such as increased speed and the ability to express toxic proteins. These systems are gaining traction due to their application in high-throughput screening and enzyme engineering, bolstered by recent technological advancements and product launches.

North America leads the protein expression market, driven by a robust healthcare infrastructure and intense R&D activities. The region's growth is fueled by the increasing acceptance of gene and monoclonal antibody-based therapies, particularly in cancer treatment. The market is characterized by a fragmented landscape with several key players, including Agilent Technologies, Bio-Rad Technologies, and Thermo Fisher Scientific, among others. These companies offer a broad range of products and cater to major end users such as research laboratories and biotechnology firms. The ongoing innovation and strategic product launches by these market leaders continue to propel the growth of the protein expression market globally.

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Global Protein Expression Market Size - Table of Contents

  1. 1. MARKET DYNAMICS

    1. 1.1 Market Overview

    2. 1.2 Market Drivers

      1. 1.2.1 Rising R&D Activity in the Pharmaceutical Sector

      2. 1.2.2 Escalation in the Biologics Market

      3. 1.2.3 Government Support for Proteomics and Genomics Research

    3. 1.3 Market Restraints

      1. 1.3.1 High Cost of Protein Expression Systems

      2. 1.3.2 Lack of Effective Systems for Post-translational Modifications

    4. 1.4 Porter's Five Forces Analysis

      1. 1.4.1 Threat of New Entrants

      2. 1.4.2 Bargaining Power of Buyers/Consumers

      3. 1.4.3 Bargaining Power of Suppliers

      4. 1.4.4 Threat of Substitute Products

      5. 1.4.5 Intensity of Competitive Rivalry

  2. 2. MARKET SEGMENTATION (Market Size by Value - USD million)

    1. 2.1 By Product

      1. 2.1.1 Reagents and Kits

        1. 2.1.1.1 Cell-free Expression

        2. 2.1.1.2 Bacterial Expression

        3. 2.1.1.3 Yeast Expression

        4. 2.1.1.4 Algal Expression

        5. 2.1.1.5 Insect Expression

        6. 2.1.1.6 Mammalian Expression

        7. 2.1.1.7 Other Expression Systems

      2. 2.1.2 Service

      3. 2.1.3 Other Products

    2. 2.2 By Application

      1. 2.2.1 Therapeutic

      2. 2.2.2 Industrial

      3. 2.2.3 Research

    3. 2.3 By End User

      1. 2.3.1 Academia

      2. 2.3.2 Biotechnology and Pharmaceuticals Companies

      3. 2.3.3 Contract Research Organizations (CROs)

    4. 2.4 By Geography

      1. 2.4.1 North America

        1. 2.4.1.1 United States

        2. 2.4.1.2 Canada

        3. 2.4.1.3 Mexico

      2. 2.4.2 Europe

        1. 2.4.2.1 Germany

        2. 2.4.2.2 United Kingdom

        3. 2.4.2.3 France

        4. 2.4.2.4 Italy

        5. 2.4.2.5 Spain

        6. 2.4.2.6 Rest of Europe

      3. 2.4.3 Asia-Pacific

        1. 2.4.3.1 China

        2. 2.4.3.2 Japan

        3. 2.4.3.3 India

        4. 2.4.3.4 Australia

        5. 2.4.3.5 South Korea

        6. 2.4.3.6 Rest of Asia-Pacific

      4. 2.4.4 Middle-East and Africa

        1. 2.4.4.1 GCC

        2. 2.4.4.2 South Africa

        3. 2.4.4.3 Rest of Middle-East and Africa

      5. 2.4.5 South America

        1. 2.4.5.1 Brazil

        2. 2.4.5.2 Argentina

        3. 2.4.5.3 Rest of South America

Global Protein Expression Market Size FAQs

The Global Protein Expression Market size is expected to reach USD 2.88 billion in 2024 and grow at a CAGR of 8.23% to reach USD 4.29 billion by 2029.

In 2024, the Global Protein Expression Market size is expected to reach USD 2.88 billion.

Protein Expression Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)