High-Performance Liquid Chromatography (HPLC) Market Size
| Study Period | 2019 - 2029 |
| Market Size (2024) | USD 5 Billion |
| Market Size (2029) | USD 6.20 Billion |
| CAGR (2024 - 2029) | 4.45 % |
| Fastest Growing Market | Asia Pacific |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
High-Performance Liquid Chromatography (HPLC) Market Analysis
The High-Performance Liquid Chromatography Market size is estimated at USD 5 billion in 2024, and is expected to reach USD 6.20 billion by 2029, growing at a CAGR of 4.45% during the forecast period (2024-2029).
Factors such as advancements in HPLC technologies and the surge in usage of HPLC in pharmaceutical and bio-pharmaceutical companies are expected to drive the market's growth during the forecast period. For instance, according to the study published in the Global Journal of Medical Pharmaceutical and Biomedical Update in September 2023, high-performance liquid chromatography (HPLC) analyzes unknown compounds, providing faster resolution times, superior peak shapes, consistent responses, and enhanced precision. The benefits associated with HPLC in identifying new compounds are anticipated to increase its adoption for research applications, bolstering the market growth.
Also, according to the study published in Pharmacological Reports in March 2023, the high-performance liquid chromatography with fluorescence detection (HPLC-FLD) method presents benefits such as reduced analysis costs and increased equipment availability compared to liquid chromatography-mass spectrometry (LC-MS). Therefore, the advantages of HPLC over other analytical techniques, such as low cost and increased availability of equipment, are anticipated to increase its adoption, thereby propelling the market growth.
Moreover, several key market players have also been interested in developing and manufacturing innovative HPLC-based systems for various laboratory functions, including diagnostics. For instance, in February 2022, Shimadzu Corporation launched the Nexera XS inert high-performance liquid chromatograph globally. The Nexera XS inert incorporates rust-resistant materials and nonmetallic materials that limit the adsorption of molecules to provide stable measurements of biopharmaceuticals and medium molecule pharmaceuticals. Such launches are expected to propel market growth during the forecast period.
Therefore, advancements in HPLC technologies, the benefits of HPLC over other analytical techniques in identifying new compounds, and the surge in HPLC usage in pharmaceutical and biopharmaceutical companies are expected to drive the market's growth. However, the lack of skilled personnel and the high cost of HPLC systems will likely hinder the market's growth during the forecast period.
High-Performance Liquid Chromatography (HPLC) Market Trends
The Consumables Segment is Expected to Hold a Significant Share in the High-Performance Liquid Chromatography (HPLC) Market
HPLC consumables are the columns, reagents, tubes, and other products used for high-performance liquid chromatography techniques. Due to the advancements in column technologies and pumps, the segment is anticipated to grow at significant rates. The pharmaceutical and biopharmaceutical companies manufacturing HPLC systems are expected to grow significantly due to the increasing need to develop new therapeutics to address the growing prevalence of chronic diseases worldwide and increase government expenditure in the research and development of biotechnology.
For instance, according to a study published by Analytical Liquid Chromatography in May 2022, the chromatographic column is essential to HPLC separation. Significant progress has been made in developing columns with better performance to provide better separation, a shorter separation time, resilience to a broader pH range of the mobile phase, longer lifetime, use of lower volumes of the mobile phase, etc. Such advancements in these columns are expected to drive segmental growth.
Recent advances by the market players in researching and developing novel HPLC techniques also add to the market's growth. For instance, in February 2022, Thermo Fisher Scientific launched a new portfolio of high-performance chromatography and mass spectrometry consumables called SureStart, which includes a new collection of caps, vials, inserts, kits, well plates, and mats. This portfolio is compatible with all add-ons and chromatography autosamplers, allowing analysts to use the new portfolio in all systems. Such research and developments in HPLC techniques are expected to propel the market growth during the forecast period.
North America is Expected to Hold a Significant Share in the Market During the Forecast Period
The rise in the adoption of highly advanced techniques and systems in manufacturing high-performance liquid chromatography (HPLC) and the technological advancements made in chromatographic studies is expected to boost the market's growth in North America.
The benefits offered by HPLC, such as accuracy in results during the identification of samples, are anticipated to boost the market growth in the United States. For instance, according to the study published in Molecules Journal in January 2024, researchers are exploring various chromatographic methods, particularly reverse phase (RP), to separate neurotransmitters (NTs) and metabolites, and HPLC facilitates the direct analysis of intracerebral microdialysis samples bypassing the need for complex derivatization. Therefore, the benefits offered by this technique are anticipated to surge the market demand due to the precise detection of intracerebral microdialysis samples.
The launch of innovative HPLC systems by the key market players also adds to the market's growth. For instance, in March 2023, Waters Corporation launched the Alliance iS, an intelligent HPLC System. It is crafted to tackle compliance risks head-on, boasting advanced error detection, troubleshooting capabilities, and a user-friendly interface. When combined with Waters' Empower Chromatography Software and eConnect HPLC Columns, the Alliance iS boosts precision and slashes common errors by a significant 40%. Therefore, such HPLC devices ensure accuracy and help quality control laboratories consistently achieve quality, safety, compliance, and timely delivery goals.
Thus, the increasing necessity for high-performance liquid chromatography (HPLC) and critical initiatives adopted by the market players are anticipated to foster the market during the forecast period.
High-Performance Liquid Chromatography Industry Overview
The high-performance liquid chromatography (HPLC) market is fragmented due to the presence of several companies operating globally and regionally. Factors contributing to the competition include the launch of innovative HPLC devices and the rising adoption of HPLC in research and development. Some of the key players operating in the market include Merck KGaA, Bio-Rad Laboratories Inc., Mitsubishi Chemical Corporation, Tosoh Corporation, and Danaher Corporation (Cytiva).
High-Performance Liquid Chromatography Market Leaders
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Merck KGaA
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Bio-Rad Laboratories, Inc.
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Mitsubishi Chemical Corporation
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Tosoh Corporation
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Danaher Corporation (Cytiva)
*Disclaimer: Major Players sorted in no particular order
High-Performance Liquid Chromatography Market News
- April 2024: Waters Corporation launched the Alliance iS Bio HPLC System, designed to address the operational and analytical challenges in biopharma quality control (QC) laboratories.
- February 2024: Telescope Innovations Corp. forged an integration partnership with Shimadzu Scientific Instruments Inc., renowned for its analytical instrumentation in chemistry R&D. The collaboration focuses on merging Telescope’s premier offering, the DirectInject-LC, with Shimadzu’s High-Performance Liquid Chromatography (HPLC) systems.
High-Performance Liquid Chromatography (HPLC) Market Report - Table of Contents
1. INTRODUCTION
- 1.1 Study Assumptions and Market Definition
- 1.2 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
- 4.1 Market Overview
-
4.2 Market Drivers
- 4.2.1 Advancements in HPLC Technologies
- 4.2.2 The Surge in Usage of HPLC in Pharmaceutical and Biopharmaceutical Companies
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4.3 Market Restraints
- 4.3.1 High Cost of the HPLC Systems
- 4.3.2 Lack of Skilled Professionals
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4.4 Porter's Five Forces Analysis
- 4.4.1 Threat of New Entrants
- 4.4.2 Bargaining Power of Buyers/Consumers
- 4.4.3 Bargaining Power of Suppliers
- 4.4.4 Threat of Substitute Products
- 4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION (Market Size by Value - in USD)
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5.1 By Product Type
- 5.1.1 Instruments
- 5.1.1.1 Systems
- 5.1.1.2 Detectors
- 5.1.1.3 Pumps
- 5.1.1.4 Other Instruments
- 5.1.2 Consumables
- 5.1.3 Accessories
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5.2 By Application
- 5.2.1 Protein Expression
- 5.2.2 Cloning
- 5.2.3 Other Applications
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5.3 By End User
- 5.3.1 Pharma Bio-pharmaceutical Companies
- 5.3.2 Contract Research Organizations
- 5.3.3 Academic Institutions
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5.4 Geography
- 5.4.1 North America
- 5.4.1.1 United States
- 5.4.1.2 Canada
- 5.4.1.3 Mexico
- 5.4.2 Europe
- 5.4.2.1 Germany
- 5.4.2.2 United Kingdom
- 5.4.2.3 France
- 5.4.2.4 Italy
- 5.4.2.5 Spain
- 5.4.2.6 Rest of Europe
- 5.4.3 Asia-Pacific
- 5.4.3.1 China
- 5.4.3.2 Japan
- 5.4.3.3 India
- 5.4.3.4 Australia
- 5.4.3.5 South Korea
- 5.4.3.6 Rest of Asia-Pacific
- 5.4.4 Middle East and Africa
- 5.4.4.1 GCC
- 5.4.4.2 South Africa
- 5.4.4.3 Rest of Middle East and Africa
- 5.4.5 South America
- 5.4.5.1 Brazil
- 5.4.5.2 Argentina
- 5.4.5.3 Rest of South America
6. COMPETITIVE LANDSCAPE
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6.1 Company Profiles
- 6.1.1 Merck KGaA
- 6.1.2 Bio-Rad Laboratories Inc.
- 6.1.3 Mitsubishi Chemical Corporation
- 6.1.4 Tosoh Corporation
- 6.1.5 Danaher Corporation (Cytiva)
- 6.1.6 Agilent Technologies Inc.
- 6.1.7 PerkinElmer Inc.
- 6.1.8 Gilson Inc.
- 6.1.9 Thermo Fisher Scientific
- 6.1.10 Shimadzu Corporation
- 6.1.11 Waters
- 6.1.12 Hitachi High-Tech Corporation
- 6.1.13 Hamilton Company
- *List Not Exhaustive
7. MARKET OPPORTUNITIES AND FUTURE TRENDS
** Subject To AvailablityHigh-Performance Liquid Chromatography Industry Segmentation
As per the report's scope, high-performance liquid chromatography (HPLC) is used to separate, identify, and quantify the components in a given mixture. HPLC is one type of column chromatography in which the components are separated using solubility.
The high-performance liquid chromatography (HPLC) market is segmented by product type, application, end user, and geography. By product type, the market is segmented into instruments, consumables, and accessories. By instruments, the market is segmented into systems, detectors, pumps, and other instruments. By application, the market is segmented into protein expression, cloning, and other applications. By end user, the market is segmented into pharma biopharmaceutical companies, contract research organizations, and academic institutions. By geography, the market is segmented into North America, Europe, Asia-Pacific, the Middle East and Africa, and South America. The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD) for the above segments.
| By Product Type | Instruments | Systems |
| Detectors | ||
| Pumps | ||
| Other Instruments | ||
| By Product Type | Consumables | |
| Accessories | ||
| By Application | Protein Expression | |
| Cloning | ||
| Other Applications | ||
| By End User | Pharma Bio-pharmaceutical Companies | |
| Contract Research Organizations | ||
| Academic Institutions | ||
| Geography | North America | United States |
| Canada | ||
| Mexico | ||
| Geography | Europe | Germany |
| United Kingdom | ||
| France | ||
| Italy | ||
| Spain | ||
| Rest of Europe | ||
| Geography | Asia-Pacific | China |
| Japan | ||
| India | ||
| Australia | ||
| South Korea | ||
| Rest of Asia-Pacific | ||
| Geography | Middle East and Africa | GCC |
| South Africa | ||
| Rest of Middle East and Africa | ||
| Geography | South America | Brazil |
| Argentina | ||
| Rest of South America |
High-Performance Liquid Chromatography (HPLC) Market Research FAQs
How big is the High-Performance Liquid Chromatography Market?
The High-Performance Liquid Chromatography Market size is expected to reach USD 5 billion in 2024 and grow at a CAGR of 4.45% to reach USD 6.20 billion by 2029.
What is the current High-Performance Liquid Chromatography Market size?
In 2024, the High-Performance Liquid Chromatography Market size is expected to reach USD 5 billion.
Who are the key players in High-Performance Liquid Chromatography Market?
Merck KGaA, Bio-Rad Laboratories, Inc., Mitsubishi Chemical Corporation, Tosoh Corporation and Danaher Corporation (Cytiva) are the major companies operating in the High-Performance Liquid Chromatography Market.
Which is the fastest growing region in High-Performance Liquid Chromatography Market?
Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).
Which region has the biggest share in High-Performance Liquid Chromatography Market?
In 2024, the North America accounts for the largest market share in High-Performance Liquid Chromatography Market.
What years does this High-Performance Liquid Chromatography Market cover, and what was the market size in 2023?
In 2023, the High-Performance Liquid Chromatography Market size was estimated at USD 4.78 billion. The report covers the High-Performance Liquid Chromatography Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the High-Performance Liquid Chromatography Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.
High-performance Liquid Chromatography Industry Report
Statistics for the 2024 High-performance Liquid Chromatography market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. High-performance Liquid Chromatography analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.
