High-Resolution Melting Analysis Market - Growth, Trends, COVID-19 Impact, and Forecasts (2024 - 2029)

The High-Resolution Melting Analysis Market is Segmented by Product and Service (Reagents and Consumables, Instruments, Software, and Services), Application (SNP Genotyping, Mutation Discovery, Pathogen Identification, and Other Applications), End-user (Research Laboratories and Academic Institutes, Pharmaceutical and Biotechnology Companies, and Other End-users), and Geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The report offers the value (in USD million) for the above segments.

High-Resolution Melting Analysis Market Size

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High-Resolution Melting Analysis Market Summary
Study Period 2021 - 2029
Market Size (2024) USD 265.59 Million
Market Size (2029) USD 327.92 Million
CAGR (2024 - 2029) 4.31 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

High-Resolution Melting Analysis Market Major Players

*Disclaimer: Major Players sorted in no particular order

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High-Resolution Melting Analysis Market Analysis

The High-Resolution Melting Analysis Market size is estimated at USD 265.59 million in 2024, and is expected to reach USD 327.92 million by 2029, growing at a CAGR of 4.31% during the forecast period (2024-2029).

The High-Resolution Melting (HRM) analysis is one of the novel techniques that help researchers understand the variations in nucleic acid sequences. Therefore, this technique was widely used during the COVID-19 pandemic. The HRM analysis is used to differentiate the various types of viruses and their composition. The researchers used HRM analysis to discriminate between the SARS-CoV-2 Omicron variants BA.1 and BA.2. Similarly, mutations in the coronavirus were studied with the help of HRM analysis during the pandemic. As per the September 2022 data published by Biochemistry and Biophysics Journal, it was observed that HRM analysis played a key role while differentiating between various strains of the coronavirus. It also contributed largely to understanding the characteristics of the coronavirus and its nuclear composition. Hence, with the effectiveness of HRM analysis, it is believed that the market studied was positively affected during the pandemic. Moreover, even after the pandemic, there is a growing use of HRM analysis which may drive market growth in the post-pandemic era.

The primary factor contributing to the market's growth is the increase in genetic disorders and infectious diseases. According to the WHO 2021 data, approximately 50,000 people die daily from contagious diseases. 30 new diseases have surfaced in the last 20 years, threatening the health of hundreds of millions of people. The rising burden of infectious diseases globally contributes mainly to market growth. Furthermore, the growing usage of HRM (High-Resolution Melting) in identifying pathogens and the advantages of HRM over other genotyping techniques are boosting the market growth. However, the HRM analysis's technical limitations are the market growth's major drawback.

Furthermore, the increasing occurrence of rare genetic diseases is augmenting the demand for novel techniques, such as HRM analysis, to understand the cause of the disease and provide better treatments. The research suggests that around 70% of rare diseases have genetic causes. Data published by Research Centre for Medical Genetics in August 2021 indicates that there were more than 45,000 people across the rural areas of Europe with rare hereditary diseases. Similarly, as per the Orphanet portal of rare diseases, around 10,500 rare diseases are registered worldwide as of 2022. With an increasing rare genetic disease burden, it is expected that the use of HRM analysis will increase, which is believed to propel market growth.

However, technical limitations associated with HRM analysis are expected to hinder market growth to some extent.

High-Resolution Melting Analysis Market Trends

This section covers the major market trends shaping the High-Resolution Melting Analysis Market according to our research experts:

SNP Genotyping Expected to Witness Strong Growth

SNP genotyping is a technique that analyzes genomic sequence variations. These single-base substitutions are typically detected using real-time PCR, microarrays, or next-generation sequencing (NGS) techniques.

Genomics is widening its range of applications in biotechnology and social science. For instance, the genetic diversity of a population or the heterogeneity of an individual for any hereditary condition with a recessive inheritance pattern can be used to predict the health and conservation of the population. This data can also help determine the effects of evolutionary processes and pick up genetic patterns of a specific population, including human and animal life.

Additionally, the increasing prevalence of new infectious, chronic, and other types of diseases will boost the market's growth. For instance, as per the GLOBOCAN 2020 report that estimated the incidence and mortality of 36 cancers in 185 countries globally, there were an estimated 19.3 million new cases of cancer and about 10 million deaths due to cancer across the world.

Translational research has revolutionized the treatment of different chronic and fatal diseases leading to the rise in demand and acceptance of personalized and precision medicine. These treatment therapies have opened a whole new application area for SNP genotyping as the medicine or therapies are developed per the patient's genomic structure, which requires the analysis of the patient's genome sequence first. The National Cancer Institute of the United States webcasts a report every year that represents the development of a new and advanced approach for analyzing tumors, which holds the potential to bring precision medicine to a broader range of people. Therefore, with the rising genomics and SNP genotyping methods, HRM analysis is expected to increase in the coming years.

High-Resolution Melting Analysis Market - Estimated Number of Cancer Cases, United States, 2022

North America Expected to Witness Notable Growth

North America is expected to dominate the overall market throughout the forecast period. The market growth is due to the factors such as the presence of key players, the high prevalence of genetic and infectious diseases in the region, and the established healthcare infrastructure. Furthermore, beneficial government initiatives and an increase in the number of research partnerships are some of the factors that drive market growth. The United States has the maximum share in this region due to supportive healthcare policies, the high number of patients, and a developed healthcare market.

The American Cancer Society estimated about 1.9 million new cancer cases to be diagnosed in the United States in 2022. More than 16.9 million people in the United States were living with a history of cancer and were alive as of 2022. With the rising number of cancer cases across the country, it is believed that the use of HRM analysis will increase, contributing mainly to market growth.

Various government bodies, such as the National Human Genome Research Institute, United States (NHGRI), have been supporting research related to human genome sequencing while funding research related to the genome's structure, function, and role in health and diseases. Moreover, these organizations support studies on genome research's ethical, legal, and social implications (ELSI). Also, the initiation by several general hospitals and other concerned organizations in the area of preventive disease by genomics will complement the market's growth, as well as newer advances and product launches. For instance, in March 2020, the Massachusetts General Hospital announced the launch of new preventive genomics clinics to assist patients in better understanding, preventing, and predicting diseases using their genetic information.

Therefore, with the increasing focus on genomics, the HRM analysis market is expected to witness substantial growth over the forecast period.

High-Resolution Melting Analysis Market- Growth Rate by Region

High-Resolution Melting Analysis Industry Overview

The High-Resolution Melting analysis market is moderately competitive and consists of several major players. Some of the international companies which are present in the market are Thermo Fisher Scientific, Inc., Bio-Rad Laboratories, Inc., F. Hoffman-La Roche Ltd, Qiagen NV, Agilent Technologies, Inc., Idaho Technology, Inc., Illumina, Inc., Kapa Biosystems, Azura Genomics, and Canon.

High-Resolution Melting Analysis Market Leaders

  1. Thermo Fisher Scientific, Inc.

  2. Bio-Rad Laboratories, Inc.

  3. F. Hoffman-La Roche Ltd.

  4. Qiagen N.V.

  5. Agilent Technologies, Inc.

*Disclaimer: Major Players sorted in no particular order

High Resolution Melting Analysis Market Competitive Landscape.png
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High-Resolution Melting Analysis Market News

  • July 2022: Indonesia's Minister of Health launched a molecular diagnostic kit with High-Resolution Melting (HRM) analysis for colorectal cancer made by Bio Farma.
  • May 2022: AMSBIO launched new pathogens detection kits in its portfolio.

High-Resolution Melting Analysis Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions & Market Definition
  • 1.2 Scope Of The Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Rising Prevalence of Genetic Disorders and Infectious Diseases
    • 4.2.2 Advantages of HRM over Other Genotyping Technologies
    • 4.2.3 Use of HRM in Pathogen Identification
  • 4.3 Market Restraints
    • 4.3.1 Technical Limitations Associated With HRM
  • 4.4 Industry Attractiveness - Porter's Five Forces Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION (Market Size - Value in USD Million)

  • 5.1 By Product and Service
    • 5.1.1 Reagents and Consumables
    • 5.1.2 Instruments
    • 5.1.3 Software and Services
  • 5.2 By Application
    • 5.2.1 SNP Genotyping
    • 5.2.2 Mutation Discovery
    • 5.2.3 Pathogen Identification
    • 5.2.4 Other Applications
  • 5.3 By End-user
    • 5.3.1 Research Laboratories and Academic Institutes
    • 5.3.2 Pharmaceutical and Biotechnology Companies
    • 5.3.3 Other End-users
  • 5.4 By Geography
    • 5.4.1 North America
    • 5.4.1.1 United States
    • 5.4.1.2 Canada
    • 5.4.1.3 Mexico
    • 5.4.2 Europe
    • 5.4.2.1 Germany
    • 5.4.2.2 United Kingdom
    • 5.4.2.3 France
    • 5.4.2.4 Italy
    • 5.4.2.5 Spain
    • 5.4.2.6 Rest of Europe
    • 5.4.3 Asia-Pacific
    • 5.4.3.1 China
    • 5.4.3.2 Japan
    • 5.4.3.3 India
    • 5.4.3.4 Australia
    • 5.4.3.5 South Korea
    • 5.4.3.6 Rest of Asia-Pacific
    • 5.4.4 Middle East and Africa
    • 5.4.4.1 GCC
    • 5.4.4.2 South Africa
    • 5.4.4.3 Rest of Middle East and Africa
    • 5.4.5 South America
    • 5.4.5.1 Brazil
    • 5.4.5.2 Argentina
    • 5.4.5.3 Rest of South America

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Thermo Fisher Scientific, Inc.
    • 6.1.2 Bio-Rad Laboratories, Inc.
    • 6.1.3 Qiagen NV
    • 6.1.4 Agilent Technologies, Inc.
    • 6.1.5 Illumina, Inc.
    • 6.1.6 F. Hoffmann-La Roche AG
    • 6.1.7 Azura Genomics
    • 6.1.8 Canon Inc.
    • 6.1.9 bioMérieux SA
    • 6.1.10 Meridian Bioscience Inc.
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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High-Resolution Melting Analysis Industry Segmentation

HRM analysis is a relatively new, post-PCR analysis method used to identify variations in nucleic acid sequences. The method is based on detecting small differences in PCR melting curves. It is enabled by improved dsDNA-binding dyes used in conjunction with real-time PCR instrumentation, precise temperature ramp control, and advanced data capture capabilities. 

The High-Resolution Melting Analysis Market is Segmented by Product and Service (Reagents and Consumables, Instruments, Software, and Services), Application (SNP Genotyping, Mutation Discovery, Pathogen Identification, and Other Applications), End-user (Research Laboratories and Academic Institutes, Pharmaceutical and Biotechnology Companies, and Other End-users), and Geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The report offers the value (in USD million) for the above segments.

By Product and Service Reagents and Consumables
Instruments
Software and Services
By Application SNP Genotyping
Mutation Discovery
Pathogen Identification
Other Applications
By End-user Research Laboratories and Academic Institutes
Pharmaceutical and Biotechnology Companies
Other End-users
By Geography North America United States
Canada
Mexico
By Geography Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
By Geography Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
By Geography Middle East and Africa GCC
South Africa
Rest of Middle East and Africa
By Geography South America Brazil
Argentina
Rest of South America
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High-Resolution Melting Analysis Market Research FAQs

The High-Resolution Melting Analysis Market size is expected to reach USD 265.59 million in 2024 and grow at a CAGR of 4.31% to reach USD 327.92 million by 2029.

In 2024, the High-Resolution Melting Analysis Market size is expected to reach USD 265.59 million.

Thermo Fisher Scientific, Inc., Bio-Rad Laboratories, Inc., F. Hoffman-La Roche Ltd., Qiagen N.V. and Agilent Technologies, Inc. are the major companies operating in the High-Resolution Melting Analysis Market.

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).

In 2024, the North America accounts for the largest market share in High-Resolution Melting Analysis Market.

In 2023, the High-Resolution Melting Analysis Market size was estimated at USD 254.62 million. The report covers the High-Resolution Melting Analysis Market historical market size for years: 2021, 2022 and 2023. The report also forecasts the High-Resolution Melting Analysis Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.

High-Resolution Melting Analysis Industry Report

Statistics for the 2024 High-Resolution Melting Analysis market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. High-Resolution Melting Analysis analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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High-Resolution Melting Analysis Market - Growth, Trends, COVID-19 Impact, and Forecasts (2024 - 2029)