Market Trends of Global Human Growth Hormone (HGH) Industry
This section covers the major market trends shaping the Human Growth Hormone (HGH) Market according to our research experts:
The Turner Syndrome Segment is Expected to Hold a Significant Market Share Over the Forecast Period
Turner syndrome is a rare chromosomal disorder that affects females. It is characterized by the partial or complete loss of one of the X chromosomes. The symptoms of Turner syndrome include a wide neck and a low or indistinct hairline, a tendency to develop high blood pressure, minor eye problems, drooping of the eyelids, and an under-active thyroid gland.
Individuals with Turner syndrome are at higher risk of severe illnesses from the COVID-19 virus. In addition, Turner syndrome patients often suffer from congenital heart disease, including having a bicuspid aortic valve. Heart disease is an underlying medical condition that can result in severe complications from COVID-19.
According to a research article by Xiaoxiao Cui et al. published in the Intractable & Rare Diseases Research 2018, Turner syndrome (TS) is a relatively common type of human chromosomal aberration that occurs in 1:2,500 live female births. It is highly prevalent in China.
Since Turner syndrome is associated with many complications related to heart, autoimmune disorders, mental health issues, hearing loss, infertility, and pregnancy complications, the demand for treatment involving growth hormones is increasing, which is boosting the market growth.
Increasing awareness about early diagnosis and treatment of Turner syndrome by various public and private organizations is expected to boost the market growth. For instance, non-profit organizations such as Turner Syndrome Support Society United Kingdom, Turner Syndrome Society of the United States, and Turner Syndrome Foundation celebrate 'Turner Syndrome Awareness Month' in February every year and launched a nationwide campaign to spread awareness about the condition.
Furthermore, increasing research and development in the development of effective therapeutics for Turner syndrome (TS) show a positive impact on the market growth. For instance, as per the research study published in the Intractable & Rare Diseases Research 2018, the next generation of treatment for Turner syndrome (TS) will be based on stem cells and regenerative medicine. Thus, considering the above factors, the market is expected to witness significant growth over the forecast period.
North America is Expected to Dominate the Market Over the Forecast Period
The major factors driving the market growth in the United States include increasing research and development activities, favorable reimbursement policies, established healthcare infrastructure, significant government initiatives, and growing healthcare awareness.
As per the Foundation for Prader-Willi Research registry data August 2020, in people with Prader-Willi syndrome, COVID-19 had an impact on access to medical care and therapies due to COVID-19-related restrictions in the United States. In addition, COVID-19 related restrictions also had an impact on temporary access to physical, occupational, speech, and psychological therapies. There was a 60-80% decline in access to Prader-Willi Syndrome-related therapies.
According to a research article by Jessica Bohonowych et al., published in the Genes Journal 2019, Prader-Willi syndrome (PWS) is a rare genetic disorder with an estimated prevalence of approximately 10,000 to 20,000 living individuals in the United States.
As per the American Academy of Pediatrics, growth hormone deficiency is a rare condition that affects less than one in 3,000 to one in 10,000 children in the United States. Recombinant growth hormone has been widely available for chronic renal insufficiency, growth hormone deficiency (GHD), gestational age or intrauterine growth retardation, Turner's syndrome, Prader-Willi syndrome, and cachexia in the United States.
Furthermore, increasing awareness about growth hormone deficiencies and treatment is expected to boost the market growth. For instance, every year, the International Coalition of Organizations Supporting Endocrine Patients (ICOSEP) celebrates Children's Growth Awareness Day to spread awareness about the early diagnosis and treatment of growth hormone disorders.
Increasing research and development activities in the development of effective therapeutics are resulting in the increasing number of pipeline drugs. For instance, in October 2019, Pfizer Inc. and its partner OPKO Health Inc. announced that its Phase III study investigating Somatrogon in pre-pubertal children with human growth hormone met its primary endpoint of non-inferiority to daily somatropin. Thus, owing to the above factors, North America is expected to register growth over the forecast period.
