Market Trends of Idiopathic Pulmonary Fibrosis Industry
Pirfenidone is Expected to Hold a Significant Share in the Global Idiopathic Pulmonary Fibrosis Market Over the Forecast Period
Pirfenidone is an orally administered drug with antifibrotic, anti-inflammatory, and antioxidant effects. This drug is used to slow the disease progression in patients with idiopathic pulmonary fibrosis (IPF). Unlike other therapies, pirfenidone is an oral medication that provides patients convenience and ease of administration. It has a favorable safety profile and is generally well-tolerated, making it a suitable option for long-term treatment.
The rising research and development activities and growing adoption of strategic initiatives such as mergers, acquisitions, partnerships, and investments by key market players associated with the drug pirfenidone allow companies to strengthen their product portfolios and enhance distribution networks, thereby contributing to the studied market growth over the study period. For instance, according to an article published by the Journal of Thoracic Disease, in March 2023, a trial has been registered at the UMIN Clinical Trials Registry for perioperative pirfenidone therapy in patients with non-small cell lung cancer combined with idiopathic pulmonary fibrosis to confirm the preventative effect against postoperative acute exacerbation.
Furthermore, per the study article published in the NIH in 2021, pirfenidone provides survival benefits for patients with idiopathic pulmonary fibrosis (IPF). Hence, the rising research and development activities are expected to drive segmental growth. Additionally, the companies are involved in strategic developments such as product launches, acquisitions and collaboration to expand their footprint, which is expected to drive segmental growth. For instance, in June 2022, Accord Healthcare, Inc reported the addition of Pirfenidone to its solid oral products portfolio in the United States. This new drug is therapeutically equivalent to Genentech's Esbriet and is approved to treat idiopathic pulmonary fibrosis (IPF).
Hence, owing to the advantages of pirfenidone over other drug types, ongoing research and development activities, and new product launches, it is expected to hold a significant market share during the forecast period.
North America is Expected to Hold a Significant Share in the Market Over the Forecast Period
The market for idiopathic pulmonary fibrosis in North America is expected to hold a significant market share owing to the rising burden of patients diagnosed with idiopathic pulmonary fibrosis and the robust healthcare infrastructure to treat idiopathic pulmonary fibrosis. For instance, in January 2022, in the United States, the median age of newly diagnosed patients is 62 years, and 54% are male. According to an article published by Springer Healthcare Communications in January 2023, the adjusted prevalence rates of idiopathic pulmonary fibrosis in North America were 2.40 to 2.98 per 10,000 people. Hence, the high burden of the disease is expected to drive market growth.
Additionally, the strategic initiatives key market players take to strengthen their product portfolios and enhance distribution networks contribute to regional market growth. For instance, in May 2022, PureTech Health plc reported the presentation of additional data for PureTech's LYT-100 (deupirfenidone) at the American Thoracic Society 2022 International Conference. The data support the upcoming registration-enabling studies in which PureTech plans to investigate LYT-100 in patients with idiopathic pulmonary fibrosis (IPF) at the scheduled 550 mg three times daily dose (TID) as well as a dose with a higher total drug exposure than the currently approved dose of pirfenidone to evaluate if higher exposure could translate into improved efficacy. Such initiatives undertaken by market players are anticipated to boost market growth.
Furthermore, product launches, partnerships, and mergers and acquisitions will help the companies expand their product offering and geographical footprints, thereby contributing to the lucrative growth of the market. For instance, in February 2022, Boehringer Ingelheim reported that the US FDA granted Breakthrough Therapy Designation to its novel investigational therapy, BI 1015550, for treating idiopathic pulmonary fibrosis (IPF).
Hence, owing to the factors such as the rising burden of idiopathic pulmonary fibrosis and strategic initiative, the market studied is expected to grow over the forecast period in the region.
