Market Trends of Interferons Industry
The Leukemia Segment is Expected to Hold a Significant Market Share During the Forecast Period
Interferon alpha is often used in treating chronic myeloid leukemia (CML). The segment is expected to show stable growth during the forecast period due to the high burden of leukemia and rising product approvals and launches by market players.
According to the American Cancer Society (ACS) 2024 report, 1.0 million new cancer cases were diagnosed in the United States by the first half of 2024. Out of the reported new cancer cases, leukemia was reported with 62,770 new cases, and lymphoma with 89,190 new cases.
Additionally, the Leukemia Foundation's 2023 update reveals that in 2023, 19,400 Australians received a diagnosis of blood cancers, including leukemia, lymphoma, and myeloma. This was equivalent to 53 people daily or one person every 27 minutes. The same source stated that 135,000 individuals were living with blood cancer in Australia in 2023, and more than 275,000 Australians are expected to be living with blood cancer by 2035. Thus, the high burden of leukemia is expected to bolster the segment growth during the forecast period.
Additionally, ongoing research and development activities for interferon therapy in treating leukemia are expected to drive market innovation and growth during the forecast period. For instance, in February 2024, the University of Pittsburgh announced a Phase 2 interferon-γ (IFN-γ) trial in combination with donor leukocyte infusion (DLI). The trial targets relapsed acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) post-allogeneic hematopoietic stem cell transplantation (alloSCT). Based on the positive results of the previous Phase 1 trial, this Phase 2 study intends to strengthen its findings by gathering leukemia cells before and after in vivo IFN-γ therapy. Therefore, these ongoing clinical trials are anticipated to contribute to the growth of this field.
Therefore, owing to the high burden of leukemia, the company's research and development for developing an innovative product are anticipated to propel the segment's growth during the forecast period.
North America is Expected to Hold a Significant Market Share During the Forecast Period
North America is expected to hold a significant share of the interferons market due to the high burden of cancer coupled with developed medical and healthcare establishments and the launch of advanced products in the region.
The high burden of hepatitis in the region is expected to propel the growth of the market. For instance, as per Center for Disease Control and Prevention data updated in April 2024, the United States reported 13,300 new cases of hepatitis B in 2022, highlighting a significant public health concern that requires ongoing monitoring and intervention. Thus, the high burden of hepatitis B is expected to increase demand for the treatment, with interferons contributing to the market growth.
Interferon alpha treats several cancers, including malignant melanoma and renal cell carcinoma. It boosts the immune system's capacity to identify and eliminate cancer cells. With cancer incidence rates increasing globally, the need for effective treatment options, including interferons, drives market demand. For instance, according to the American Cancer Society 2024, 81,610 new kidney and renal pelvis cases were diagnosed in the United States. Most kidney cancers are renal cell carcinomas. Hence, the high burden of renal cell carcinoma is anticipated to propel the market growth during the forecast period.
Moreover, the growth of the market in North America is fueled by the presence of key players, increasing awareness initiatives, and the launch of innovative products in the region. Moreover, in May 2024, CytomX Therapeutics Inc. and Merck (called MSD outside the United States and Canada) entered a collaboration and supply agreement for a clinical trial. This trial is CytomX's first-in-human Phase 1 study, evaluating the clinical efficacy of CX-801. CX-801 is a dually-masked interferon alpha2b cytokine, being tested in conjunction with Merck's renowned anti-PD-1 therapy, KEYTRUDA (pembrolizumab). Interferon alpha-2 b is a potent cytokine recognized for its clinical efficacy against various cancer types. Thus, such developments for interferons in the region are expected to boost the growth of the market during the forecast period.
Thus, the high burden of hepatitis, renal cell carcinoma, and strategic activities by the market players are expected to boost the market in North America during the forecast period.
