Membrane Chromatography Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)

The Membrane Chromatography Market Report is Segmented by Product (Capsules and Cartridges, Syringe Filters, Membrane Filters, Filter Plates, Spin Columns, and Other Consumables and Accessories), Technique (Ion Exchange Membrane Chromatography, Affinity Membrane Chromatography, and Hydrophobic Interaction Membrane Chromatography (HIMC)), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The Report Offers the Value in USD for the Above Segments.

Membrane Chromatography Market Size

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Membrane Chromatography Market Summary
Study Period 2019 - 2029
Market Size (2024) USD 0.3 Billion
Market Size (2029) USD 0.6 Billion
CAGR (2024 - 2029) 16.00 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Membrane Chromatography Market Major Players

*Disclaimer: Major Players sorted in no particular order

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Membrane Chromatography Market Analysis

The Membrane Chromatography Market size is estimated at USD 0.3 billion in 2024, and is expected to reach USD 0.6 billion by 2029, growing at a CAGR of 16% during the forecast period (2024-2029).

Membrane chromatography is a well-established bioprocessing technology routinely used to capture large particles such as viruses and viral vectors and in polishing steps for removing DNA, host cell protein impurities (HCP), and viruses. The rising demand for biopharmaceuticals and increasing regulatory scrutiny on the cleaning validation of downstream purification processes are the major factors for the growth of this market. For instance, in December 2022, Shimadzu collaborated with the University Medical Center Göttingen, Germany, to develop new clinical laboratory methods using liquid chromatography-mass spectrometry for therapeutic drug monitoring (TDM) analysis. Thus, such collaborations are expected to fuel market growth during the forecast period.

Also, the pharmaceutical industry's growing research and development spending to develop advanced membrane chromatography systems and the adoption of such products across the pharmaceutical and biopharmaceutical industries is anticipated to increase, propelling market growth. For instance, Merck & Co. invested USD 30.5 billion in R&D during FY 2023, representing 50.8% of the total revenue. Notably, a significant portion of the funding is dedicated to partnerships and acquisitions, highlighting a focus on collaboration and accelerating drug development. Hence, rising R&D spending by pharma companies creates a surge in complex research, driving demand for membrane chromatography during the manufacturing process of drugs during the forecast period.

Moreover, the increase in R&D spending in the biopharmaceutical industry aided in the growth of the market. For example, according to the Pharmaceutical Industry and Global Health Facts and Figures 2022 report, the biopharmaceutical industry's annual research and development spending was 8.1 times greater than other industries. According to the same source, over USD 202 billion is estimated to be spent worldwide on biopharmaceutical research and development in 2024. Thus, with high R&D spending, the development of new drugs will increase, ultimately fueling the adoption of membrane chromatography systems and consumables across biopharmaceutical industries boosting market growth.

Thus, the demand for membrane chromatography technologies is propelled by the development of new drugs, a growing need for high purity, technological advancements, and an emphasis on efficient upstream processing across the biopharmaceutical industry. However, the limited use of membrane chromatography in large-scale manufacturing is expected to restrain the growth of the market during the forecast period.

Membrane Chromatography Market Trends

Ion Exchange Membrane Chromatography is Expected to Hold a Significant Share of the Market

Ion exchange chromatography (IC) is a process that separates ions and polar molecules based on their affinity for the ion exchanger. It works on almost any charged molecule, including large proteins, small nucleotides, and amino acids.

The segment is anticipated to witness significant growth during the forecast period owing to increasing new drug approvals and new product launches by the key players.

The rising new drug approvals, including biologics, for the treatment of various chronic diseases are anticipated to fuel the adoption of ion-exchange chromatography systems to purify proteins and other biomolecules. For instance, as per data published by the Center for Drug Evaluation and Research (CDER) in January 2024, about 55 new drugs were approved in 2023, marking a nearly 50% increase compared to 2022. Each new drug candidate requires a robust purification process to ensure its safety and efficacy. With more drugs being approved, the demand for efficient and scalable purification techniques like ion exchange membrane chromatography will rise, boosting the segment growth.

Ion exchange membrane chromatography has wide applications in antibody polishing and virus purification owing to its advantages, including scalability, robustness, disposable nature, high throughput, and rapid processing. Thus, the advantages offered by ion exchange chromatography are anticipated to fuel its adoption across the biopharmaceutical industry, propelling segment growth.

Also, the growing number of new product launches supporting wide applications in drug development and purification is another factor bolstering the market growth. For instance, in December 2022, CD Bioparticles launched a range of ion exchange chromatography resins with enhanced loading capacity, ultra-high resolution, and mechanical solid strengths, suitable for the purification of small molecular weight molecules, covering small proteins, polypeptides, nucleic acids, and antibiotics.

Moreover, the membrane chromatography market is receiving a significant boost from a surge in R&D expenditure in the United States. For instance, the National Science Foundation (NSF) data published in January 2024 showed a notable surge in the United States research and development (R&D) expenditure, boosting the development of the membrane chromatography market. This is expected to drive the demand for ion exchange membrane chromatography systems and consumables, augmenting segment growth.

Thus, the segment is expected to grow during the forecast period due to increasing drug approvals, product launches, and R&D expenditures.

Membrane Chromatography Market - Drug Approval by Food and Drug Administration, United States, 2021-2023

North America is Expected is Expected to Hold a Significant Market Share of the Membrane Chromatography Market

North America is expected to witness significant growth during the forecast period, owing to the rising burden of chronic diseases boosting the demand for novel drugs in the market and the presence of well-structured and developed healthcare systems. This region also promotes pharmaceutical research and development and has high healthcare expenditures. As a result of these policies, many companies are encouraged to operate in this region.

The rising number of clinical trials conducted by the biopharmaceutical and pharmaceutical companies is expected to fuel the adoption of membrane chromatography, bolstering the market growth. For instance, a report by the National Library of Medicine (NLM) indicates that there were 20,465 clinical trials actively recruiting participants across the United States in 2023. As promising drug candidates advance through the clinical phase, the demand for membrane chromatography systems and consumables for reliable and scalable purification propels market growth.

Additionally, investment in biopharmaceuticals will create a strong demand for efficient and reliable purification technologies like membrane chromatography over the coming years. For instance, Johnson & Johnson (J&J) increased its investment in R&D for 2023, allocating USD 15.09 billion. Notably, the United States boasts the most conducive environment for pharmaceutical research, development, and commercialization, characterized by minimal market barriers.

Moreover, the incidence of diseases such as cancer, cardiovascular diseases, and diabetes is increasing, further boosting the demand for novel drugs in the market. For instance, as per the Canadian Cancer Statistics released in November 2023, an estimated 239,100 Canadians were diagnosed with cancer in 2023. The report further highlighted the fact that roughly 1 in 4 Canadians are expected to succumb to the disease. The rising incidence of diseases like cancer and cardiovascular diseases fuels the demand for new biopharmaceuticals, propelling the adoption of membrane chromatography as a critical tool for the purification of drugs.

Moreover, the rising launches of innovative membrane chromatography systems and consumables contribute significantly to the market growth. For instance, in May 2024, AGC Biologics' research and development team made a significant breakthrough in the field of monoclonal antibody (mAb) purification. The focus is on single-use membrane chromatography, a revolutionary technology poised to disrupt the traditional protein A purification process. This creates substantial cost savings and helps bring therapies to the market, thereby driving the market's growth.

Thus, factors such as increasing research and development (R&D) by pharmaceuticals, demand for drug approvals, and product innovation by key players are contributing to the faster growth of the membrane chromatography market and are expected to boost the market during the forecast period.

Membrane Chromatography Market - Growth Rate by Region

Membrane Chromatography Industry Overview

The membrane chromatography market is moderately consolidated in nature due to the majority of the global key players. Market leaders with more funds for research and better distribution systems have established their position in the market. Moreover, Asia-Pacific is witnessing the emergence of some small players due to the rise of awareness. This has also helped the market grow. Some key market players are 3M, Thermo Fisher Scientific Inc., Merck KGaA, Danaher Corporation, and Sartorius AG.

Membrane Chromatography Market Leaders

  1. 3M

  2. Merck KGaA

  3. Danaher Corporation

  4. Sartorius AG

  5. Thermo Fisher Scientific Inc.

*Disclaimer: Major Players sorted in no particular order

Membrane Chromatography Market Concentration
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Membrane Chromatography Market News

  • June 2024: Ecolab partnered with Repligen Corporation (RGEN) to launch a new protein A chromatography resin called DurA Cycle. This resin is designed for large-scale purification processes in biopharmaceuticals. This marks a significant step forward in the long-term collaboration between Purolite and Repligen, showcasing Ecolab's commitment to innovation in bioprocessing.
  • February 2024: Thermo Fisher Scientific launched the Dionex Inuvion Ion Chromatography (IC) system. This innovative instrument promises to simplify and streamline ion analysis for laboratories of all sizes. The Dionex Inuvion IC system prioritizes user-friendliness. Its intuitive design makes ion analysis more accessible, even for labs with less experienced personnel.

Membrane Chromatography Market Report - Table of Contents

1. INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2. RESEARCH METHODOLOGY

3. EXECUTIVE SUMMARY

4. MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Demand for Biopharmaceuticals
    • 4.2.2 Increasing Regulatory Scrutiny on the Cleaning Validation of Downstream Purification Processes
    • 4.2.3 Increasing R&D Expenditure in the Biopharmaceutical Industry
  • 4.3 Market Restraints
    • 4.3.1 Limited Use of Membrane Chromatography Products in Large-Scale Manufacturing
  • 4.4 Porter's Five Force Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5. MARKET SEGMENTATION (Market Size by Value - USD million)

  • 5.1 By Product
    • 5.1.1 Capsules and Cartridges
    • 5.1.2 Syringe Filters
    • 5.1.3 Membrane Filters
    • 5.1.4 Filter Plates
    • 5.1.5 Spin Columns
    • 5.1.6 Other Consumables and Accessories
  • 5.2 By Technique
    • 5.2.1 Ion Exchange Membrane Chromatography
    • 5.2.2 Affinity Membrane Chromatography
    • 5.2.3 Hydrophobic Interaction Membrane Chromatography (HIMC)
  • 5.3 Geography
    • 5.3.1 North America
    • 5.3.1.1 United States
    • 5.3.1.2 Canada
    • 5.3.1.3 Mexico
    • 5.3.2 Europe
    • 5.3.2.1 Germany
    • 5.3.2.2 United Kingdom
    • 5.3.2.3 France
    • 5.3.2.4 Italy
    • 5.3.2.5 Spain
    • 5.3.2.6 Rest of Europe
    • 5.3.3 Asia-Pacific
    • 5.3.3.1 China
    • 5.3.3.2 Japan
    • 5.3.3.3 India
    • 5.3.3.4 Australia
    • 5.3.3.5 South Korea
    • 5.3.3.6 Rest of Asia-Pacific
    • 5.3.4 Middle East and Africa
    • 5.3.4.1 GCC
    • 5.3.4.2 South Africa
    • 5.3.4.3 Rest of Middle East and Africa
    • 5.3.5 South America
    • 5.3.5.1 Brazil
    • 5.3.5.2 Argentina
    • 5.3.5.3 Rest of South America

6. COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Danaher Corporation
    • 6.1.2 GVS SpA
    • 6.1.3 Membrane Solutions
    • 6.1.4 Merck KGaA
    • 6.1.5 Purilogics
    • 6.1.6 Restek Corporation
    • 6.1.7 Sartorius AG
    • 6.1.8 Thermo Fisher Scientific
    • 6.1.9 Asahi Kasei Corporation
  • *List Not Exhaustive

7. MARKET OPPORTUNITIES AND FUTURE TRENDS

**Subject to Availability
**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments
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Membrane Chromatography Industry Segmentation

As per the scope, membrane chromatography is a technique that combines the principles of membrane filtration and chromatography for separating biomolecules. It utilizes a microfiltration membrane containing pores with chromatography ligands attached to the inner surface.

The membrane chromatography market is segmented by product, technique, and geography. By product, the market is segmented into capsules and cartridges, syringe filters, membrane filters, filter plates, spin columns, and other consumables and accessories. By technique, the market is segmented into ion exchange membrane chromatography, affinity membrane chromatography, and hydrophobic interaction membrane chromatography (HIMC). By geography, the market is segmented into North America, Europe, Asia-Pacific, the Middle East and Africa, and South America. The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD) for the above segments.

By Product Capsules and Cartridges
Syringe Filters
Membrane Filters
Filter Plates
Spin Columns
Other Consumables and Accessories
By Technique Ion Exchange Membrane Chromatography
Affinity Membrane Chromatography
Hydrophobic Interaction Membrane Chromatography (HIMC)
Geography North America United States
Canada
Mexico
Geography Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Geography Asia-Pacific China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Geography Middle East and Africa GCC
South Africa
Rest of Middle East and Africa
Geography South America Brazil
Argentina
Rest of South America
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Membrane Chromatography Market Research FAQs

The Membrane Chromatography Market size is expected to reach USD 0.3 billion in 2024 and grow at a CAGR of 16% to reach USD 0.6 billion by 2029.

In 2024, the Membrane Chromatography Market size is expected to reach USD 0.3 billion.

3M, Merck KGaA, Danaher Corporation, Sartorius AG and Thermo Fisher Scientific Inc. are the major companies operating in the Membrane Chromatography Market.

Asia Pacific is estimated to grow at the highest CAGR over the forecast period (2024-2029).

In 2024, the North America accounts for the largest market share in Membrane Chromatography Market.

In 2023, the Membrane Chromatography Market size was estimated at USD 0.25 billion. The report covers the Membrane Chromatography Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Membrane Chromatography Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.

Membrane Chromatography Industry Report

Statistics for the 2023 Membrane Chromatography market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. Membrane Chromatography analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.

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Membrane Chromatography Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)