Membrane Chromatography Market Size (2024 - 2029)

The membrane chromatography market is projected to experience significant growth due to increasing demand in biopharmaceuticals and heightened regulatory scrutiny on purification processes. This market expansion is driven by the pharmaceutical industry's rising research and development expenditures, which are focused on advanced membrane chromatography systems. Collaborations and partnerships within the industry further contribute to market growth by accelerating drug development. Despite these positive trends, the market's expansion may be constrained by the limited application of membrane chromatography in large-scale manufacturing.

Market Size of Membrane Chromatography Industry

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Membrane Chromatography Market Summary
Study Period 2019 - 2029
Market Size (2024) USD 0.3 Billion
Market Size (2029) USD 0.6 Billion
CAGR (2024 - 2029) 16.00 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Membrane Chromatography Market Major Players

*Disclaimer: Major Players sorted in no particular order

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Membrane Chromatography Market Analysis

The Membrane Chromatography Market size is estimated at USD 0.3 billion in 2024, and is expected to reach USD 0.6 billion by 2029, growing at a CAGR of 16% during the forecast period (2024-2029).

Membrane chromatography is a well-established bioprocessing technology routinely used to capture large particles such as viruses and viral vectors and in polishing steps for removing DNA, host cell protein impurities (HCP), and viruses. The rising demand for biopharmaceuticals and increasing regulatory scrutiny on the cleaning validation of downstream purification processes are the major factors for the growth of this market. For instance, in December 2022, Shimadzu collaborated with the University Medical Center Göttingen, Germany, to develop new clinical laboratory methods using liquid chromatography-mass spectrometry for therapeutic drug monitoring (TDM) analysis. Thus, such collaborations are expected to fuel market growth during the forecast period.

Also, the pharmaceutical industry's growing research and development spending to develop advanced membrane chromatography systems and the adoption of such products across the pharmaceutical and biopharmaceutical industries is anticipated to increase, propelling market growth. For instance, Merck & Co. invested USD 30.5 billion in R&D during FY 2023, representing 50.8% of the total revenue. Notably, a significant portion of the funding is dedicated to partnerships and acquisitions, highlighting a focus on collaboration and accelerating drug development. Hence, rising R&D spending by pharma companies creates a surge in complex research, driving demand for membrane chromatography during the manufacturing process of drugs during the forecast period.

Moreover, the increase in R&D spending in the biopharmaceutical industry aided in the growth of the market. For example, according to the Pharmaceutical Industry and Global Health Facts and Figures 2022 report, the biopharmaceutical industry's annual research and development spending was 8.1 times greater than other industries. According to the same source, over USD 202 billion is estimated to be spent worldwide on biopharmaceutical research and development in 2024. Thus, with high R&D spending, the development of new drugs will increase, ultimately fueling the adoption of membrane chromatography systems and consumables across biopharmaceutical industries boosting market growth.

Thus, the demand for membrane chromatography technologies is propelled by the development of new drugs, a growing need for high purity, technological advancements, and an emphasis on efficient upstream processing across the biopharmaceutical industry. However, the limited use of membrane chromatography in large-scale manufacturing is expected to restrain the growth of the market during the forecast period.

Membrane Chromatography Industry Segmentation

As per the scope, membrane chromatography is a technique that combines the principles of membrane filtration and chromatography for separating biomolecules. It utilizes a microfiltration membrane containing pores with chromatography ligands attached to the inner surface.

The membrane chromatography market is segmented by product, technique, and geography. By product, the market is segmented into capsules and cartridges, syringe filters, membrane filters, filter plates, spin columns, and other consumables and accessories. By technique, the market is segmented into ion exchange membrane chromatography, affinity membrane chromatography, and hydrophobic interaction membrane chromatography (HIMC). By geography, the market is segmented into North America, Europe, Asia-Pacific, the Middle East and Africa, and South America. The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD) for the above segments.

By Product
Capsules and Cartridges
Syringe Filters
Membrane Filters
Filter Plates
Spin Columns
Other Consumables and Accessories
By Technique
Ion Exchange Membrane Chromatography
Affinity Membrane Chromatography
Hydrophobic Interaction Membrane Chromatography (HIMC)
Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa
GCC
South Africa
Rest of Middle East and Africa
South America
Brazil
Argentina
Rest of South America
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Membrane Chromatography Market Size Summary

The membrane chromatography market is poised for significant growth, driven by the increasing demand for biopharmaceuticals and the need for efficient purification processes. This bioprocessing technology is essential for capturing large particles and removing impurities such as DNA and host cell proteins. The market's expansion is fueled by the pharmaceutical industry's heightened research and development investments, aimed at developing advanced membrane chromatography systems. Collaborations, such as those between Shimadzu and the University Medical Center Göttingen, are expected to further propel market growth. Despite the limited use of membrane chromatography in large-scale manufacturing, its adoption is anticipated to rise due to technological advancements and the growing emphasis on high-purity drug development.

The ion exchange chromatography segment is expected to witness substantial growth, supported by the increasing number of new drug approvals and product launches. This segment's scalability and efficiency make it a preferred choice for purifying proteins and biomolecules. The market is also benefiting from rising R&D expenditures, particularly in the United States, which is enhancing the development and adoption of membrane chromatography systems. North America is projected to experience significant growth due to its robust healthcare infrastructure and high healthcare spending. The increasing incidence of chronic diseases is driving the demand for novel drugs, further boosting the market. Key players like 3M, Thermo Fisher Scientific Inc., and Merck KGaA are leading the market, with ongoing innovations and strategic partnerships contributing to its expansion.

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Membrane Chromatography Market Size - Table of Contents

  1. 1. MARKET DYNAMICS

    1. 1.1 Market Overview

    2. 1.2 Market Drivers

      1. 1.2.1 Increasing Demand for Biopharmaceuticals

      2. 1.2.2 Increasing Regulatory Scrutiny on the Cleaning Validation of Downstream Purification Processes

      3. 1.2.3 Increasing R&D Expenditure in the Biopharmaceutical Industry

    3. 1.3 Market Restraints

      1. 1.3.1 Limited Use of Membrane Chromatography Products in Large-Scale Manufacturing

    4. 1.4 Porter's Five Force Analysis

      1. 1.4.1 Threat of New Entrants

      2. 1.4.2 Bargaining Power of Buyers/Consumers

      3. 1.4.3 Bargaining Power of Suppliers

      4. 1.4.4 Threat of Substitute Products

      5. 1.4.5 Intensity of Competitive Rivalry

  2. 2. MARKET SEGMENTATION (Market Size by Value - USD million)

    1. 2.1 By Product

      1. 2.1.1 Capsules and Cartridges

      2. 2.1.2 Syringe Filters

      3. 2.1.3 Membrane Filters

      4. 2.1.4 Filter Plates

      5. 2.1.5 Spin Columns

      6. 2.1.6 Other Consumables and Accessories

    2. 2.2 By Technique

      1. 2.2.1 Ion Exchange Membrane Chromatography

      2. 2.2.2 Affinity Membrane Chromatography

      3. 2.2.3 Hydrophobic Interaction Membrane Chromatography (HIMC)

    3. 2.3 Geography

      1. 2.3.1 North America

        1. 2.3.1.1 United States

        2. 2.3.1.2 Canada

        3. 2.3.1.3 Mexico

      2. 2.3.2 Europe

        1. 2.3.2.1 Germany

        2. 2.3.2.2 United Kingdom

        3. 2.3.2.3 France

        4. 2.3.2.4 Italy

        5. 2.3.2.5 Spain

        6. 2.3.2.6 Rest of Europe

      3. 2.3.3 Asia-Pacific

        1. 2.3.3.1 China

        2. 2.3.3.2 Japan

        3. 2.3.3.3 India

        4. 2.3.3.4 Australia

        5. 2.3.3.5 South Korea

        6. 2.3.3.6 Rest of Asia-Pacific

      4. 2.3.4 Middle East and Africa

        1. 2.3.4.1 GCC

        2. 2.3.4.2 South Africa

        3. 2.3.4.3 Rest of Middle East and Africa

      5. 2.3.5 South America

        1. 2.3.5.1 Brazil

        2. 2.3.5.2 Argentina

        3. 2.3.5.3 Rest of South America

Membrane Chromatography Market Size FAQs

The Membrane Chromatography Market size is expected to reach USD 0.3 billion in 2024 and grow at a CAGR of 16% to reach USD 0.6 billion by 2029.

In 2024, the Membrane Chromatography Market size is expected to reach USD 0.3 billion.

Membrane Chromatography Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)