Nucleic Acid Isolation, Quantitation, and Purification Market Size (2024 - 2029)

Nucleic Acid Isolation & Purification Market Analysis

The Nucleic Acid Isolation, Quantitation, and Purification Market size is estimated at USD 5.11 billion in 2024, and is expected to reach USD 8.03 billion by 2029, growing at a CAGR of 9.44% during the forecast period (2024-2029).

COVID-19 significantly impacted the nucleic acid isolation, quantitation, and purification market during its initial phase owing to various factors, such as the shortage of reagents and equipment due to the surge in nucleic acid screening for COVID-19 detection. For instance, as per the article published in January 2022 in Frontiers, a total of 7,118 people received 10,377 SARS-CoV-2 nucleic acid tests in one district of Jiulongpo district of China during the pandemic. Furthermore, in October 2022 in PubMed, routine nucleic acid screening in the general population evolved into a substantial and effective prevention and control measure as a result of the increased number of asymptomatic infection cases. Numerous advanced techniques are being used in the post-pandemic setting for nucleic isolation, quantification, and separation, which is expected to increase the demand for more reagents and equipment. For instance, as per the article published in May 2022 in Springer, researchers suggested the purification of Plasmid DNA using affinity chromatography, with amino acids acting as particular ligands to rectify the challenges associated with the purification process in biopharmaceutical manufacturing. Thus, the market is anticipated to witness growth due to the rise in research activities in nucleic acid isolation, quantitation, and purification along with an increase in development in genomic research.

Factors such as an increase in demand for sequencing platforms in clinical diagnostics, a rise in genomics research, and growth in funding for research and development in molecular biology are anticipated to drive the market growth over the forecast period. For instance, in October 2022, Chennai-based start-up MagGenome introduced a new technology that makes DNA extraction easy. The procedure is simple and clear, which creates iron nanoparticles, induces them to bind to DNA, and then applies a magnetic field to extract both proteins and RNA. Furthermore, research studies focusing on nucleic acid quantitation are expected to boost market growth over the forecast period. For instance, as per the article published in September 2022 in the MDPI journal, accurate DNA quantification is a very important method within molecular biology and UV spectrometry and fluorometry are widely used to quantify DNA. The study demonstrated that combining a spectrophotometric and fluorometric approach is advised to provide information on a sample's purity and dsDNA content. Thus, research is likely to require more nucleic acid extraction, quatitation and isolation products, thereby driving market growth over the forecast period.

Furthermore, the technological advancements in the research associated with the isolation and purification of nucleic acid are likely to boost market growth over the forecast period. For instance, as per the article published in April 2022 in Taylor and Francis Online, the majority of commercial nucleic acid isolation kits available are silica-based. In the study, researchers focused on new methods to enhance silica-based protocols for nucleic acid purification. The study intended to highlight the current needs to be addressed by innovative purification techniques based on silica materials.

Furthermore, product launches and collaboration by the key players are anticipated to strengthen the competition in the market. For instance, in April 2022, Purigen Biosystems, Inc., a provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, launched the Ionic Cells to Pure DNA Kit. The new kit was optimized to allow users of the Ionic Purification System to extract increased yields of high-quality DNA from WBCs, peripheral blood mononuclear cells (PBMCs), and cultured or sorted cells.

Hence, due to the rise in research activities, funding in the field of nucleic acid isolation, quantitation, and purification, and an increase in reagent product launches, the nucleic acid isolation quantitation, and purification market is anticipated to witness growth over the forecast period. However, the high cost of instruments and reagents and low penetration in Emerging markets are expected to restrain the market growth over the forecast period.

Nucleic Acid Isolation & Purification Industry Segmentation

Nucleic acid isolation is the process by which DNA and/or RNA are separated from proteins, membranes, and other cellular materials. Nucleic acid quantitation is a typical procedure in molecular biology to ascertain the average quantities and purity of DNA or RNA contained in a combination. Nucleic acids can be purified by dipping in-house-made dipsticks into just three solutions: the extract (to bind the nucleic acids), a wash buffer (to remove impurities), and the amplification reaction (to elute the nucleic acids).

The Nucleic Acid Isolation, Quantitation, and Purification Market is Segmented by Technology (Column-based Purification, Magnetic Bead-based Purification, and Reagent-based Purification), Product (Kits and Reagents (Nucleic Acid Isolation and Purification, Nucleic Acid Quantitation (DNA Quantitation Kits, RNA Quantitation Kits)), Equipment (Nucleic Acid Isolation and Purification, Nucleic Acid Quantitation (Spectrophotometer, Fluorometer)), Other Products), Application (Total RNA Isolation and Purification, mRNA Isolation and Purification, microRNA Isolation and Purification, Plasmid DNA Isolation and Purification, Genomic DNA Isolation and Purification, Blood DNA Isolation and Purification, PCR Clean-up, Biobanking, Clinical Research, Forensics, Drug Development, Others), End-user (Hospitals, Academia, Pharmaceutical/Biotechnology Industry, CRO), and Geography (North America, Europe, Asia-Pacific, Middle East, and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across significant regions, globally. The report offers the value (in USD million) for the above-mentioned segments.