Organoids Market Size (2024 - 2029)

The organoids market is experiencing significant growth, driven by increased research and development activities, particularly in the context of drug development and infectious disease research. The COVID-19 pandemic accelerated the adoption of organoids due to their ability to mimic actual organs and provide relevant cellular responses, which proved valuable in vaccine research and treatment identification. Post-pandemic, the market continues to expand as organoids are increasingly utilized in clinical trials and studies across various chronic diseases and disorders. Technological advancements and a deeper understanding of disease mechanisms are further propelling the demand for organoid models in pharmaceutical research, despite some limitations in their functional similarity to actual organs.

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Market Size of Organoids Industry

Organoids Market Summary
Study Period 2019 - 2029
Base Year For Estimation 2023
CAGR 17.10 %
Fastest Growing Market Asia-Pacific
Largest Market North America
Market Concentration High

Major Players

Organoids Market Major Players

*Disclaimer: Major Players sorted in no particular order

Organoids Market Analysis

The Organoids Market is projected to register a CAGR of 17.1% during the forecast period.
The COVID-19 pandemic had a significant impact on the organoids market. The increasing number of research and development activities for the introduction of the COVID-19 vaccine within a very limited time resulted in the higher adoption of organoids during the pandemic. The resemblance with actual organs, cell tropism, cell viability, and others are some of the key factors for the significant adoption of organoids during drug development at the time of the pandemic. For instance, an article published by the National Center for Biotechnology Information (NCBI) in February 2022, reported that organoids offered a significant pace in the research of COVID-19 by offering proper cellular heterogeneity, viral susceptibility, and appropriate host cell responses. Additionally, specific organoids were reported to be effective while identifying the treatment option for COVID-19. For instance, an article published by Springer Nature Limited in May 2021, reported that lung organoids had shown promising results while detecting the treatment options for the SARS-COV-2 virus during the pandemic.

Moreover, a research journal published by Springer Nature Limited in April 2022, reported that human pluripotent stem cell-derived airway organoids have shown certain specific characteristics of the SARS-COV-2 virus as well showed effectiveness while evaluating the options to limit the spread of the virus. This results in the increased use of organoids in the research field during the pandemic and fosters the market's growth. However, in the post-pandemic situation, the research studies and clinical trials increased significantly involving organoids. For instance, according to ClinicalTrials.gov, a total of 47 studies were reported involving organoids from 1st March 2021 till 3rd January 2023. Also, an article published by MDPI in June 2022, titled '3D Human Organoids: The Next 'Viral' Model for the Molecular Basis of Infectious Diseases,' reported that organoids were proven to be efficacious in the research of a number of disorders, including COVID-19, HIV, Hepatitis B, Hepatitis C among others and gained its traction in the research of infectious disease in the post-pandemic situation. The above-mentioned factors are anticipated to contribute to the further growth of the market during the forecast period.
There are certain factors that are driving the market growth, including the rising prevalence of chronic diseases, the rising number of research on drug development involving organoids, and technological advancements in the development of organoids. The prevalence of chronic diseases, including cardiovascular disease, chronic kidney disease, and cancer, among others, is increasing globally. For instance, according to an article by the National Health Service (NHS) in May 2021, it was reported that an estimated 1.4 million people in the United Kingdom were suffering from atrial fibrillation in 2021. Additionally, according to a research article published by the Annals of Cancer Epidemiology in 2021, an estimated 235,760 new lung cancer cases were diagnosed in the United States in 2021. This rising number of patients suffering from a number of chronic diseases is increasing the healthcare burden and, alternatively, increasing the research and development initiatives for the introduction of novel drugs to be used in these chronic diseases. Additionally, owing to a better understanding of the disease condition and the effect of drugs on the actual organs, the adoption of organoid models is increasing for R&D purposes. According to ClinicalTrial.gov, a study titled 'Intestinal Organoids (BIOÏDES)' started in September 2022 in France was aimed to develop a bio-collection of organoids from digestive biopsies with associated health data prior to testing them with potential therapeutic molecules for gastrointestinal disorders.
Furthermore, a number of rising initiatives in pharmaceutical research and development were observed by the major players for the development of organoids and the application of organoids to different indications, such as lung cancer, genetic abnormalities, chronic kidney disease, cardiovascular disorders, and colon cancer, among others. These initiatives are also fueling the demand for organoids in the research field. For instance, according to ClinicalTrials.gov, a total of 79 clinical studies are there for organoids till 31st December 2022. Apart from that, the latest technological advancements in the development of organoids models were further improving the outcomes of organoids in pharmaceutical research. For instance, in October 2022, AIM Biotech Pte. Ltd. introduced organiX System. This system is capable of adding vascularization and immune competence to organoids which can improve the shelf life of organoids during the research procedure.
Thus, the above-mentioned factors are attributed to the growing demand and adoption of organoids in the pharmaceutical research field and have been instrumental in the market's growth. However, certain clinical disadvantages, including functional disparities between the organoids and actual organs, are limiting the adoption rate of organoids during the study period.

Organoids Industry Segmentation

As per the scope of this report, organoids are miniature organs resembling the physical and functional properties of the actual organs. These organoids are widely used in clinical research for the development of drugs and evaluating drug toxicity, among others.

The Organoids Market is segmented by Product Type (Intestine, Liver, Stomach, Pancreas, Others), Application (Drug Discovery & Personalized Medicine, Drug Toxicity & Efficacy Testing, Regenerative Medicine, Developmental Biology, and Others), End User (Pharmaceutical & Biotechnology Companies, Contract Research Organizations, and Research Institutes) and Geography (North America, Europe, Asia-Pacific, Middle East & Africa, and South America).The report offers the value (USD million) for the above segments.

By Product Type
Intestine
Liver
Stomach
Pancrease
Others
By Application
Drug Discovery and Personalized Medicine
Drug Toxicity and Efficacy Testing
Regenerative Medicine
Developmental Biology
Others
By End User
Pharmaceutical and Biotechnology Companies
Contract Research Organisations
Research Institutes
Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle-East and Africa
GCC
South Africa
Rest of Middle East and Africa
South America
Brazil
Argentina
Rest of South America
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Organoids Market Size Summary

The organoids market is experiencing significant growth, driven by the increasing adoption of organoid technology in research and development activities, particularly in the pharmaceutical sector. The COVID-19 pandemic accelerated the use of organoids due to their ability to mimic actual organs, which proved invaluable in vaccine development and understanding viral infections. This trend has continued post-pandemic, with organoids being utilized in studies related to various infectious diseases and chronic conditions such as cancer and cardiovascular diseases. The rising prevalence of these diseases is prompting more research and development initiatives, further boosting the demand for organoids. Technological advancements in organoid development, such as the introduction of systems that enhance their functionality, are also contributing to market expansion. Despite some clinical challenges, the benefits of organoids in drug discovery and personalized medicine are fostering their adoption in these areas.

North America is expected to maintain a dominant position in the global organoids market, supported by a large patient population with chronic diseases, advanced healthcare infrastructure, and substantial research and development funding. The presence of key industry players and ongoing regulatory changes, such as the FDA Modernization Act, which reduces reliance on animal testing, are further propelling the market in this region. The organoids market is characterized by a few major players, with companies like Merck KGaA and Cellesce Ltd leading the market. Recent strategic moves, such as acquisitions and the introduction of advanced organoid systems, are enhancing the capabilities and applications of organoids in research, thereby driving market growth.

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Organoids Market Size - Table of Contents

  1. 1. MARKET DYNAMICS

    1. 1.1 Market Overview

    2. 1.2 Market Drivers

      1. 1.2.1 Increasing Number of Research and Development Activity

      2. 1.2.2 Latest Advancement in Organoids

    3. 1.3 Market Restraints

      1. 1.3.1 Certain Charecteristics Differentiation with the Actual Organs

    4. 1.4 Porter's Five Force Analysis

      1. 1.4.1 Threat of New Entrants

      2. 1.4.2 Bargaining Power of Buyers/Consumers

      3. 1.4.3 Bargaining Power of Suppliers

      4. 1.4.4 Threat of Substitute Products

      5. 1.4.5 Intensity of Competitive Rivalry

  2. 2. MARKET SEGMENTATION (Market Size by Value - USD million)

    1. 2.1 By Product Type

      1. 2.1.1 Intestine

      2. 2.1.2 Liver

      3. 2.1.3 Stomach

      4. 2.1.4 Pancrease

      5. 2.1.5 Others

    2. 2.2 By Application

      1. 2.2.1 Drug Discovery and Personalized Medicine

      2. 2.2.2 Drug Toxicity and Efficacy Testing

      3. 2.2.3 Regenerative Medicine

      4. 2.2.4 Developmental Biology

      5. 2.2.5 Others

    3. 2.3 By End User

      1. 2.3.1 Pharmaceutical and Biotechnology Companies

      2. 2.3.2 Contract Research Organisations

      3. 2.3.3 Research Institutes

    4. 2.4 Geography

      1. 2.4.1 North America

        1. 2.4.1.1 United States

        2. 2.4.1.2 Canada

        3. 2.4.1.3 Mexico

      2. 2.4.2 Europe

        1. 2.4.2.1 Germany

        2. 2.4.2.2 United Kingdom

        3. 2.4.2.3 France

        4. 2.4.2.4 Italy

        5. 2.4.2.5 Spain

        6. 2.4.2.6 Rest of Europe

      3. 2.4.3 Asia-Pacific

        1. 2.4.3.1 China

        2. 2.4.3.2 Japan

        3. 2.4.3.3 India

        4. 2.4.3.4 Australia

        5. 2.4.3.5 South Korea

        6. 2.4.3.6 Rest of Asia-Pacific

      4. 2.4.4 Middle-East and Africa

        1. 2.4.4.1 GCC

        2. 2.4.4.2 South Africa

        3. 2.4.4.3 Rest of Middle East and Africa

      5. 2.4.5 South America

        1. 2.4.5.1 Brazil

        2. 2.4.5.2 Argentina

        3. 2.4.5.3 Rest of South America

Organoids Market Size FAQs

The Organoids Market is projected to register a CAGR of 17.10% during the forecast period (2024-2029)

Merck KGaA, Cellesce Ltd, 3Dnamics Inc., R&D Systems, Inc. and Hubrecht Organoid Technology are the major companies operating in the Organoids Market.

Organoids Report Snapshots

Organoids Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)