Global Protein A Resin Market Size (2024 - 2029)

Protein A Resins Market Analysis

The Global Protein A Resin Market size is estimated at USD 1.17 billion in 2024, and is expected to reach USD 1.78 billion by 2029, growing at a CAGR of 8.69% during the forecast period (2024-2029).

According to Cancer Facts and Figures 2023 by the American Cancer Society, the number of new cancer cases in the United States was estimated to be 1.95 million in 2023, of which 1.01 million were male and 0.94 million were female. Similarly, according to the February 2022 update by the World Health Organization, cancer prevalence was high, and it was evident in the most common types of cancer in terms of new cases. The rising burden of cancer is augmenting the demand for antibodies to manage disease complications, which is expected to drive the market’s growth over the forecast period.

The number of drug discoveries and research and development activities is increasing. Monoclonal antibodies are at the forefront of modern drug development, particularly in oncology, autoimmune diseases, and infectious diseases. Its targeted nature and high efficacy have led to a surge in the development of new mAb-based therapies. This necessitates a robust and scalable purification process, making protein A resin critical for biopharmaceutical companies. For instance, according to a report published by the Society of Biological Engineering Journal in February 2023, the increased demand for efficient purification methods in the biopharmaceutical industry, where increasing drug discoveries and R&D activities fuel the need for protein A chromatography, boosted the growth of the protein A resin market. The ability to reuse protein A resins across multiple products in GMP facilities can reduce costs and improve efficiency, further propelling market growth.

According to a report published by the Monoclonal Antibody Journal in January 2024, the growing focus on monoclonal antibody therapeutics, evidenced by an increase in drug discoveries and R&D activities, is driving the demand for protein A resin, a key component in antibody purification. As more antibodies are developed for clinical use and regulatory approval, such as lecanemab (Leqembi) for Alzheimer's disease and talquetamab (Talvey) for cancer, the need for effective purification processes using protein A resin is becoming more critical.

While several factors contribute to the growth of the market, the high costs associated with protein A resin are expected to impede the growth of the market over the forecast period.

Protein A Resins Industry Segmentation

As per the scope of the report, protein A resin is an affinity chromatography medium designed for easy, one-step purification of classes, subclasses, and fragments of immunoglobulins from biological fluids and cell culture media. 

The Protein A Resin market is segmented by product type, application, end user, and geography. By product type, the market is segmented into agarose-based protein, glass or silica-based protein, and organic polymer-based protein. By application, the market is segmented into antibody purification and immunoprecipitation. By end user, the market is segmented into pharmaceutical and biopharmaceutical companies, research laboratories, and others. By geography, the market is segmented into North America, Europe, Asia-Pacific, the Middle East and Africa, and South America. The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the values (USD) for all the above segments.