SGLT2 Inhibitors Market Size
| Study Period | 2019 - 2029 |
| Market Size (2024) | USD 11.42 Billion |
| Market Size (2029) | USD 17.32 Billion |
| CAGR (2024 - 2029) | 8.68 % |
| Fastest Growing Market | Middle East and North Africa |
| Largest Market | North America |
Major Players
*Disclaimer: Major Players sorted in no particular order |
Need a report that reflects how COVID-19 has impacted this market and its growth?
SGLT2 Inhibitors Market Analysis
The Sodium-dependent Glucose Co-transporter 2 Market size is estimated at USD 11.42 billion in 2024, and is expected to reach USD 17.32 billion by 2029, growing at a CAGR of 8.68% during the forecast period (2024-2029).
The Sodium-Dependent Glucose Cotransporter 2 market benefited from the COVID-19 pandemic. People with diabetes have a weakened immune system, which is exacerbated by COVID-19. Diabetes patients are more likely than non-diabetics to have significant problems. Diabetic medicine makers took care during COVID-19 to ensure that pharmaceuticals were delivered to diabetes patients with the assistance of local governments.
"Since the start of COVID-19, our commitment to patients, our employees, and the communities where we operate has remained unchanged," NovoNordisk stated on their website. "We continue to supply our medicines and devices to people living with diabetes and other serious chronic diseases, safeguard the health of our employees, and take actions to support doctors and nurses as they work to defeat COVID-19."
SGLT-2 inhibitors, commonly known as gliflozins, are a kind of medication used to treat type 2 diabetes by lowering high blood glucose levels. SGLT-2 inhibitors have an important role in the management of cardiovascular risk factors such as blood pressure, glycemia, weight, cardiac function, and antiinflammatory action. Diabetic medications have been proposed as prospective treatments for diabetic people infected with SARS-CoV-2 during the COVID-19 epidemic. Technological advancements have increased over the period leading to several modifications either in the SGLT-2 inhibitors or the formulations being developed.
Therefore, due to increased prevalence and the aforementioned factors, the studied market is anticipated to witness growth over the analysis period.
SGLT2 Inhibitors Market Trends
Jardiance is Leading the SGLT2 Market.
Jardiance, released globally in 2014, is a once-daily oral medication used to control blood glucose levels in people with Type 2 diabetes. Jardince is gaining sales compared to Invokana, with patients preferring this drug as it has a lower risk of cardiovascular diseases when compared to other SGLT2 drugs by helping the kidneys remove glucose from the bloodstream. Jardiance accounted for more than 30% of the sales in the global SGLT2 class of drugs in the current year. Jardiance is a prescription medicine used to lower blood sugar, diet, and exercise in adults with Type 2 diabetes. It reduces the risk of cardiovascular death in adults with Type 2 diabetes who also have known cardiovascular disease. Jardiance also reduces the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure, when the heart cannot pump enough blood to the rest of the body. It is not for people with Type 1 diabetes.
Jardiance is a prescription drug used to lower blood sugar in individuals with Type 2 diabetes and to lessen the risk of cardiovascular death in adults with Type 2 diabetes who have known cardiovascular disease. It is also used in conjunction with diet and exercise. Heart attacks, strokes, and other cardiac disorders are all examples of cardiovascular illness.
Jardiance has also been shown to lower A1C in persons with Type 2 diabetes who do not have cardiovascular disease (CV disease), diet, and exercise. Jardiance may aid some people in losing weight even though it wasn't designed to do so. In a study using Jardiance alone, the average weight loss at the 10 and 25 mg doses was 2.5% and 2.8%, respectively. Jardiance also assisted some individuals in slightly lowering systolic blood pressure, which is the highest number in the blood pressure reading, when used alone or in combination with metformin, even though it was not intended to do so.
65% of the Market Share is Occupied by North America.
North America accounts for the highest Type 2 diabetic population. The growing global Type, 2 diabetes population promotes the growth of SGLT2 drugs. Prices are comparatively high in this region. Jardiance holds 50% of the market share in the US SGLT2 market. The American Diabetes Association Standards of Care has recommended empagliflozin (the active pharmaceutical ingredient in Jardiance) as the only diabetic drug that reduces the risk of cardiovascular death in adults with Type 2 diabetes.
In the United States, the prevalence of diabetes has increased dramatically during the last two decades, driven by the increased prevalence of obesity and lifestyle changes. Diabetes ranks among the fast-growing chronic diseases in the United States. About 1.75 million US citizens are diagnosed with diabetes every year. The country also has the highest obese population, a prominent cause of Type 2 diabetes.
In addition to diet and exercise, SGLT2 inhibitors, a class of FDA-approved prescription medications, are used to lower blood sugar levels in people with Type 2 diabetes. Canagliflozin, dapagliflozin, and empagliflozin are examples of drugs that are SGLT2 inhibitors. Single-ingredient formulations and combinations with other diabetes drugs, such as metformin, are available. SGLT2 inhibitors lower blood sugar levels by stimulating the kidneys to remove sugar from the body through urine. Because it has not been established that SGLT2 inhibitors are safe and effective in patients with Type 1 diabetes, the FDA has not approved their use in this population.
Most pharmaceutical companies view the United States as a premium market since they can charge more for their products than in other nations while still seeing high sales. Pharmaceutical businesses that sell pharmaceuticals benefit from the insurance program in the nation, which reimburses consumers for over 50% of the cost of prescription drugs. Due to the increased prevalence of obesity in the country, the United States is expected to lead the market throughout the forecast period.
SGLT2 Inhibitors Industry Overview
The Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market is highly consolidated, with a few significant manufacturers having a global market presence. The companies strengthen their market presence by getting approval in new forms.
SGLT2 Inhibitors Market Leaders
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Janssen Pharmaceuticals
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Eli Lilly
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Bristol Myers Squibb
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AstraZeneca Pharmaceuticals
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Astellas
*Disclaimer: Major Players sorted in no particular order
SGLT2 Inhibitors Market News
- June 2023: the U.S. Food and Drug Administration approved Jardiance (empagliflozin) and Synjardy (empagliflozin and metformin hydrochloride) as additions to diet and exercise to improve blood sugar control in children 10 years and older with type 2 diabetes. These approvals provide a new class of medicines taken by mouth to treat pediatric type 2 diabetes.
- April 2022: Nippon Boehringer Ingelheim's SGLT-2 inhibitor Jardiance (empagliflozin) obtained a label update from PMDA in Japan, allowing its use in patients with chronic heart failure with preserved ejection fraction (HFpEF) in addition to those with heart failure with reduced ejection fraction (HFrEF).
SGLT2 Inhibitors Market Report - Table of Contents
1. INTRODUCTION
- 1.1 Study Assumptions and Market Definition
- 1.2 Scope of the Study
2. RESEARCH METHODOLOGY
3. EXECUTIVE SUMMARY
4. MARKET DYNAMICS
- 4.1 Market Overview
- 4.2 Drivers
- 4.3 Restraints
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4.4 Porter's Five Forces Analysis
- 4.4.1 Bargaining Power of Suppliers
- 4.4.2 Bargaining Power of Consumers
- 4.4.3 Threat of New Entrants
- 4.4.4 Threat of Substitute Products and Services
- 4.4.5 Intensity of Competitive Rivalry
5. MARKET SEGMENTATION
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5.1 Drug
- 5.1.1 Sodium - Glucose Co-transport -2 (SGLT-2) Inhibitor
- 5.1.1.1 Invokana (Canagliflozin)
- 5.1.1.2 Jardiance (Empagliflozin)
- 5.1.1.3 Farxiga/Forxiga (Dapagliflozin)
- 5.1.1.4 Suglat (Ipragliflozin)
-
5.2 Geography
- 5.2.1 North America
- 5.2.1.1 United States
- 5.2.1.2 Canada
- 5.2.1.3 Rest of North America
- 5.2.2 Europe
- 5.2.2.1 France
- 5.2.2.2 Germany
- 5.2.2.3 Italy
- 5.2.2.4 Spain
- 5.2.2.5 United Kingdom
- 5.2.2.6 Russia
- 5.2.2.7 Rest of Europe
- 5.2.3 Latin America
- 5.2.3.1 Mexico
- 5.2.3.2 Brazil
- 5.2.3.3 Rest of Latin America
- 5.2.4 Asia-Pacific
- 5.2.4.1 Japan
- 5.2.4.2 South Korea
- 5.2.4.3 China
- 5.2.4.4 India
- 5.2.4.5 Australia
- 5.2.4.6 Vietnam
- 5.2.4.7 Malaysia
- 5.2.4.8 Indonesia
- 5.2.4.9 Philippines
- 5.2.4.10 Thailand
- 5.2.4.11 Rest of Asia-Pacific
- 5.2.5 Middle-East and Africa
- 5.2.5.1 Saudi Arabia
- 5.2.5.2 Iran
- 5.2.5.3 Egypt
- 5.2.5.4 Oman
- 5.2.5.5 South Africa
- 5.2.5.6 Rest of Middle-East and Africa
6. MARKET INDICATORS
- 6.1 Type-1 Diabetes Population
- 6.2 Type-2 Diabetes Population
7. COMPETITIVE LANDSCAPE
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7.1 COMPANY PROFILES
- 7.1.1 Eli Lilly
- 7.1.2 Janssen Pharmaceuticals
- 7.1.3 Bristol Myers Squibb
- 7.1.4 Boehringer Ingelheim
- 7.1.5 AstraZeneca
- 7.1.6 Astellas
- *List Not Exhaustive
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7.2 MARKET SHARE ANALYSIS
- 7.2.1 Eli Lilly
- 7.2.2 Janssen Pharmaceuticals
- 7.2.3 Astellas
- 7.2.4 Boehringer Ingelheim
- 7.2.5 AstraZeneca
8. MARKET OPPORTUNITIES AND FUTURE TRENDS
SGLT2 Inhibitors Industry Segmentation
A family of glucose transporters is known as sodium-dependent glucose co-transporters (also known as sodium-glucose linked transporters or SGLT2). Only the proximal renal tubules express it, which is responsible for 90% of glucose reabsorption from tubular fluid. Sodium-dependent Glucose Co-transporter 2 (SGLT 2) Market is segmented into drugs (Invokana, Jardiance, Farxiga/Forxiga, and Suglat) and Geography. The report offers the value (in USD) and volume (in Units) for the above segments.
| Drug | Sodium - Glucose Co-transport -2 (SGLT-2) Inhibitor | Invokana (Canagliflozin) |
| Jardiance (Empagliflozin) | ||
| Farxiga/Forxiga (Dapagliflozin) | ||
| Suglat (Ipragliflozin) | ||
| Geography | North America | United States |
| Canada | ||
| Rest of North America | ||
| Geography | Europe | France |
| Germany | ||
| Italy | ||
| Spain | ||
| United Kingdom | ||
| Russia | ||
| Rest of Europe | ||
| Geography | Latin America | Mexico |
| Brazil | ||
| Rest of Latin America | ||
| Geography | Asia-Pacific | Japan |
| South Korea | ||
| China | ||
| India | ||
| Australia | ||
| Vietnam | ||
| Malaysia | ||
| Indonesia | ||
| Philippines | ||
| Thailand | ||
| Rest of Asia-Pacific | ||
| Geography | Middle-East and Africa | Saudi Arabia |
| Iran | ||
| Egypt | ||
| Oman | ||
| South Africa | ||
| Rest of Middle-East and Africa |
SGLT2 Inhibitors Market Research FAQs
How big is the Sodium-dependent Glucose Co-transporter 2 Market?
The Sodium-dependent Glucose Co-transporter 2 Market size is expected to reach USD 11.42 billion in 2024 and grow at a CAGR of 8.68% to reach USD 17.32 billion by 2029.
What is the current Sodium-dependent Glucose Co-transporter 2 Market size?
In 2024, the Sodium-dependent Glucose Co-transporter 2 Market size is expected to reach USD 11.42 billion.
Who are the key players in Sodium-dependent Glucose Co-transporter 2 Market?
Janssen Pharmaceuticals, Eli Lilly, Bristol Myers Squibb, AstraZeneca Pharmaceuticals and Astellas are the major companies operating in the Sodium-dependent Glucose Co-transporter 2 Market.
Which is the fastest growing region in Sodium-dependent Glucose Co-transporter 2 Market?
Middle East and North Africa is estimated to grow at the highest CAGR over the forecast period (2024-2029).
Which region has the biggest share in Sodium-dependent Glucose Co-transporter 2 Market?
In 2024, the North America accounts for the largest market share in Sodium-dependent Glucose Co-transporter 2 Market.
What years does this Sodium-dependent Glucose Co-transporter 2 Market cover, and what was the market size in 2023?
In 2023, the Sodium-dependent Glucose Co-transporter 2 Market size was estimated at USD 10.43 billion. The report covers the Sodium-dependent Glucose Co-transporter 2 Market historical market size for years: 2019, 2020, 2021, 2022 and 2023. The report also forecasts the Sodium-dependent Glucose Co-transporter 2 Market size for years: 2024, 2025, 2026, 2027, 2028 and 2029.
SGLT2 Drugs Industry Report
Statistics for the 2024 SGLT2 Drugs market share, size and revenue growth rate, created by Mordor Intelligence™ Industry Reports. SGLT2 Drugs analysis includes a market forecast outlook to 2029 and historical overview. Get a sample of this industry analysis as a free report PDF download.
