Market Trends of Global Tacrolimus Industry
This section covers the major market trends shaping the Tacrolimus Market according to our research experts:
Immunosuppression Segment is Expected to Witness Growth over the Forecast Period
Tacrolimus medications are used in immunosuppression during transplant procedures that work by lowering the body's ability to reject a transplanted organ. The immunosuppression segment is anticipated to witness significant growth over the forecast period owing to the growing number of transplants, an increase in R&D activities for immunosuppression, and a surge in the acceptance rate of tacrolimus treatments among the patient population.
According to an article titled "Clinical significance of tacrolimus intra-patient variability on kidney transplant outcomes according to pre-transplant immunological risk" published in the National Library of Medicine in June 2021, in solid organ transplantation, the immunosuppressant tacrolimus is the cornerstone of the immunosuppressive regimen to prevent organ rejection and graft loss. According to the same source, until new therapeutic drugs become available, the only way to optimize long-term graft outcomes after kidney transplantation is to adjust current immunosuppression based on immunological risk profile. Such factors are likely to have a positive impact on the segment's growth over the analysis period.
Similarly, growth in strategic initiatives such as product launches and approvals, mergers, and acquisitions by prominent players within the market is anticipated to boost the segment's growth. For instance, in June 2020, Sandoz, a Novartis AG company, announced the availability of generic once-daily tacrolimus capsules under the brand names Conferoport in Italy and Spain and Dailiport in Germany, the United Kingdom, the Netherlands, Finland, Sweden, Estonia, Latvia, and Slovakia. Available in dosages of 0.5 mg, 1 mg, 3 mg, and 5 mg, Dailiport/Conferoport is recommended for use in adult kidney and liver transplant patients.
Thus, owing to these abovementioned factors, the immunosuppression segment is expected to register a substantial growth rate over the analysis period.
North America is Expected to Dominate the Tacrolimus Market
North America is expected to dominate the market owing to factors such as a surge in the number of organ transplants, increasing awareness regarding tacrolimus, and the presence of key manufacturers within the region. For instance, according to Health Resources and Services Administration estimates, more than 40,000 transplants were performed in 2021 in the United States alone. Furthermore, 90,483 people were on the organ transplant waiting list. Thus, this higher number of transplant procedures will ultimately increase the adoption of tacrolimus medications among the patient population, thereby driving the growth of the market in North America.
In addition, strategic initiatives and key product launches by pharmaceutical companies within the region are expected to bolster the market's growth. For instance, in July 2021, Astellas Pharma Inc. received approval from the United States Food and Drug Administration (FDA) for its supplemental New Drug Application (sNDA) for Prograf (tacrolimus) which became the first immunosuppressive drug approved in the United States. Likewise, in November 2020, Glenmark Pharmaceuticals Inc. was granted final approval by the United States Food and Drug Administration for Tacrolimus capsules USP in the strengths of 0.5 mg, 1 mg, and 5 mg. Similarly, in November 2020, Biocon Ltd. received the United States Food and Drug Administration approval for the launch of Tacrolimus capsules in the United States.
Thus, these aforesaid factors are collectively driving the growth of the tacrolimus market in the North American region.
