Global Tissue Sealants Market Size (2024 - 2029)

The tissue sealants market is projected to experience growth over the forecast period, driven by factors such as the increasing prevalence of joint and bone disorders, technological advancements in cartilage repair, and the rising geriatric population. Despite initial setbacks due to the COVID-19 pandemic, which disrupted elective surgeries and impacted market expansion, the market is expected to recover and grow. The engagement of key players in research and development, along with technological advancements and strategic partnerships, is anticipated to further enhance the market's expansion. However, challenges such as high costs and reimbursement issues may hinder growth.

Market Size of Global Tissue Sealants Industry

Tissue Sealants Market
Study Period 2019 - 2029
Base Year For Estimation 2023
Forecast Data Period 2024 - 2029
CAGR 6.90 %
Fastest Growing Market Asia Pacific
Largest Market North America

Major Players

Global Tissue Sealants Market Major Players

*Disclaimer: Major Players sorted in no particular order

Tissue Sealants Market Analysis

The tissue sealants market is expected to register a CAGR of 7% during the forecast period. 

The impact of COVID in its initial phase was adverse owing to cancellations of elective procedures including orthopedic surgeries, which hampered the market growth. For instance, an article titled "Effect of COVID-19 Pandemic on Orthopedic Surgery in Three Centers from Romania" published in the International Journal of Environmental Research and Public Health in February 2021 stated that the orthopedic specialty was one of the most severely affected because of the significant number of elective surgeries that were postponed and major surgeries with high resource demands. The orthopedic departments were transformed into COVID-19 facilities, and joint replacements in particular were stopped worldwide. It also stated that in March 2020, the Surgeon General canceled all elective surgeries in the United States of America. Therefore, COVID-19 hindered the studied market. However, as the virus affected the bone and joints of the patient, it significantly affected the manufacturing of orthopedics implants, tools, instruments, and routine ongoing research and development which is expected to boost the market growth in coming years.

In addition, the rising prevalence of joint and bone disorders around the world, technological advancements in cartilage repair/regeneration, and the rapid increase in the geriatric population are actively affecting the growth of the studied market.

According to the Organization for Ecothe nomic Co-operation and Development, September 2022 update, total knee replacement surgery conducted in 2020 was 169,116 in Germany, 61,909 in Italy, and 30,808 in United Kingdom. The high burden of knee replacement surgeries worldwide is predicted to augment the growth of tissue sealants in the coming years.

Furthermore, according to World Population Prospects 2022 report, the percentage of the population aged 65 years and over in Sub-Saharan Africa is 3.0 in 2022 and projected to be 3.3 in 2030, in Northern Africa and Western Asia it is estimated to be 5.5 in 2022, and projected to be 7.0 in 2030, in Central and Southern Asia it is estimated to be 6.4 in 2022 and projected to be 8.1 in 2030, and in Europe and Northern America, 18.7 in 2022 and projected to be 22.0 in 2030. Since bone injuries are more common in the geriatric population, the growth of the market is likely to increase as the population increases.

Additionally, the engagement of key market players and institutions in research and development in the field of tissue sealants is expected to augment the market growth. For instance, a clinical trial titled "Safety and Performance of a Synthetic Tissue Sealant in Reducing Fluid Leakage in Hepatobiliary and Pancreatic Surgery" was commenced on August 2020 and completed on April 2022. The trial was sponsored by Polyganics BV in collaboration with University Hospital-Eppendorf (UKE) Hamburg. The objective of the study was to evaluate the sealing device's efficacy in preventing bile and pancreatic juice leakage during hepato-pancreato-biliary (HPB) surgery. The rising clinical trial activities for the development of innovative solutions are projected to augment the market growth.

The advancements in technology and increasing,g product approvals, along with partnerships and acquisitions by key players are helping in the market growth. For instance, in December 2021, BD (Becton, Dickinson and Company) acquired Tissuemed, Ltd., a privately held firm that is involved in developing self-adhesive surgical sealant films. Such developments are anticipated to augment the market growth.

Therefore, owing to the aforementioned factors the studied market is anticipated to witness growth over the analysis period. however, high costs of cartilage repair procedures and reimbursement issues are likely to impede the market growth.

Tissue Sealants Industry Segmentation

As per the scope of the report, tissue sealants are agents with a clot-promoting activity that halts bleeding from injury or during surgery. The Tissue Sealants Market is segmented by Type of Sealant (Fibrin Sealants, Gelatin and Thrombin Mixtures, Polyethylene Glycol Polymers, Cyanoacrylates, Albumin, and Glutaraldehyde Tissue Sealants, and Other Types of Sealants), Application (Orthopedic, Cardiac Surgeries, Urology, Neuro Surgery, Dentistry, and Others), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions, globally. The report offers the value (in USD million) for the above segments.

Type of Sealent
Fibrin Sealants
Gelatin and Thrombin Mixtures
Polyethylene Glycol Polymers
Cyanoacrylates
Albumin and Glutaraldehyde Tissue Sealants
Other Types of Sealants
Applications
Orthopeadic
Cardiac Surgeries
Urology
Neuro Surgery
Dentistry
Others
Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa
GCC
South Africa
Rest of Middle East and Africa
South America
Brazil
Argentina
Rest of South America
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Global Tissue Sealants Market Size Summary

The tissue sealants market is poised for significant growth, driven by several key factors. The market experienced initial setbacks due to the COVID-19 pandemic, which led to the postponement of elective surgeries, particularly in orthopedics. However, the subsequent impact of the virus on bone and joint health has spurred demand for orthopedic implants and tools, thereby boosting market growth. The increasing prevalence of joint and bone disorders, coupled with technological advancements in cartilage repair and regeneration, is further propelling the market. The expanding geriatric population, which is more susceptible to bone injuries, is also a significant contributor to the market's expansion. Additionally, the active engagement of major market players in research and development, along with clinical trials aimed at developing innovative tissue sealant solutions, is expected to enhance market growth.

North America is anticipated to dominate the tissue sealants market due to a combination of factors, including a high incidence of bone and sports injuries, a growing number of hip and knee replacement surgeries, and a robust geriatric population. The region benefits from a strong presence of industry players, advanced healthcare infrastructure, and heightened awareness of available technologies among healthcare stakeholders. The market is characterized by its fragmented nature, with numerous global and regional companies competing for market share. Key players such as Avin Darou, Grünenthal, Becton, Dickinson and Company, and Johnson and Johnson Services, Inc. are actively involved in product innovations and strategic partnerships, which are expected to drive market growth. Despite challenges such as high costs and reimbursement issues, the market is set to witness substantial growth over the forecast period.

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Global Tissue Sealants Market Size - Table of Contents

  1. 1. MARKET DYNAMICS

    1. 1.1 Market Overview

    2. 1.2 Market Drivers

      1. 1.2.1 Rising Prevalence of the Joint and Bone Disorders Around the World

      2. 1.2.2 Technological Advancements in Cartilage Repair/Regeneration

      3. 1.2.3 Rapid increase in Geriatric Population

    3. 1.3 Market Restraints

      1. 1.3.1 High Costs of Cartilage Repair Procedures

      2. 1.3.2 Reimbursement Issues

    4. 1.4 Porter's Five Force Analysis

      1. 1.4.1 Threat of New Entrants

      2. 1.4.2 Bargaining Power of Buyers/Consumers

      3. 1.4.3 Bargaining Power of Suppliers

      4. 1.4.4 Threat of Substitute Products

      5. 1.4.5 Intensity of Competitive Rivalry

  2. 2. MARKET SEGMENTATION (Market Size by Value - USD million)

    1. 2.1 Type of Sealent

      1. 2.1.1 Fibrin Sealants

      2. 2.1.2 Gelatin and Thrombin Mixtures

      3. 2.1.3 Polyethylene Glycol Polymers

      4. 2.1.4 Cyanoacrylates

      5. 2.1.5 Albumin and Glutaraldehyde Tissue Sealants

      6. 2.1.6 Other Types of Sealants

    2. 2.2 Applications

      1. 2.2.1 Orthopeadic

      2. 2.2.2 Cardiac Surgeries

      3. 2.2.3 Urology

      4. 2.2.4 Neuro Surgery

      5. 2.2.5 Dentistry

      6. 2.2.6 Others

    3. 2.3 Geography

      1. 2.3.1 North America

        1. 2.3.1.1 United States

        2. 2.3.1.2 Canada

        3. 2.3.1.3 Mexico

      2. 2.3.2 Europe

        1. 2.3.2.1 Germany

        2. 2.3.2.2 United Kingdom

        3. 2.3.2.3 France

        4. 2.3.2.4 Italy

        5. 2.3.2.5 Spain

        6. 2.3.2.6 Rest of Europe

      3. 2.3.3 Asia-Pacific

        1. 2.3.3.1 China

        2. 2.3.3.2 Japan

        3. 2.3.3.3 India

        4. 2.3.3.4 Australia

        5. 2.3.3.5 South Korea

        6. 2.3.3.6 Rest of Asia-Pacific

      4. 2.3.4 Middle East and Africa

        1. 2.3.4.1 GCC

        2. 2.3.4.2 South Africa

        3. 2.3.4.3 Rest of Middle East and Africa

      5. 2.3.5 South America

        1. 2.3.5.1 Brazil

        2. 2.3.5.2 Argentina

        3. 2.3.5.3 Rest of South America

Global Tissue Sealants Market Size FAQs

The Global Tissue Sealants Market is projected to register a CAGR of 6.90% during the forecast period (2024-2029)

CryoLife, Integra LifeSciences Corporation, Becton, Dickinson and Company, Johnson and Johnson Services, Inc. (Ethicon Inc.) and CSL Behring are the major companies operating in the Global Tissue Sealants Market.

Tissue Sealants Market Size & Share Analysis - Growth Trends & Forecasts (2024 - 2029)